Effects of Pulsed Magnetic Field on the Flowing Red Blood Cells Using Microvascular Model

被引：0
作者：
Jo, Yonghyeok [1 ]
Ahn, Hyoje [1 ]
Shin, Kyunghun [1 ]
Lee, Hyunsook [1 ]
机构：
[1] Sangji Univ, Dept Oriental Biomed Engn, Wonju 220702, South Korea
来源：
IEEE TRANSACTIONS ON MAGNETICS | 2018年 / 54卷 / 11期
基金：
新加坡国家研究基金会;
关键词：
Biomagnetics; oxidative stress; pulsed magnetic field; red blood cells; IN-VIVO; AGGREGATION; VELOCITY;
D O I：
10.1109/TMAG.2018.2850927
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
We have investigated quantitatively the effects of pulsed magnetic field (PMF) stimulus on the changes of blood flow, aggregation of red blood cells (RBCs), and oxidative stress on RBCs in the micro-channel of 15 mu m in diameter, in order to understand rheological properties of RBC in the microcirculation system. Erythrocyte sedimentation rate analysis was applied to see the effect of PMF on RBCs aggregation. RBCs disaggregated after PMF stimulus were sedimented slowly compared to that before PMF. It is also observed that after PMF stimulus, aggregation of RBCs is almost loosened, and the velocity of RBCs is fast in the microvascular model. Changes in blood flow and deformation of RBCs were examined after inducing oxidative stress to the erythrocyte membrane in order to see how the magnetic field affects the oxygen transport capacity of RBCs. From our results, PMF stimulus is proposed to achieve improvement of RBCs aggregation, increase of blood velocity, and preventing RBCs from oxidative stress.
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页数：3
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