Are B-type natriuretic peptide (BNP) and N-terminal-pro-BNP useful in neonates?

被引：1
作者：
El-Khuffash, Afif [1 ]
Molloy, Eleanor J. [1 ]
机构：
[1] Natl Matern Hosp, Dept Neonatol, Dublin 2, Ireland
来源：
ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION | 2007年 / 92卷 / 04期
关键词：
PATENT DUCTUS-ARTERIOSUS; CONGESTIVE-HEART-FAILURE; UMBILICAL-CORD BLOOD; PLASMA-LEVELS; PROGNOSTIC VALUE; SEPTIC SHOCK; PEDIATRIC-PATIENTS; REFERENCE VALUES; LUNG-DISEASE; CHILDREN;
D O I：
暂无
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
B-type natriuretic peptide (BNP) and N-terminal-pro-BNP (NTpBNP) have a major role in screening and diagnosis of cardiac disease and monitoring of the treatment response in children and adults. This review discusses the evidence underpinning the potential benefits of these natriuretic peptides in neonatology. They may serve as a useful adjunct to echocardiography in the diagnosis of patent ductus arteriosus and its response to treatment and the diagnosis of persistent pulmonary hypertension of the newborn. However, more work is needed to explore the possible roles of BNP/NTpBNP in the management of sepsis and monitoring of cardiac performance in neonates.
引用
收藏
页码：320 / 324
页数：5
相关论文
共 56 条
  • [1] Implications of the natriuretic peptide system in the pathogenesis of heart failure: diagnostic and therapeutic importance
    Abassi, Z
    Karram, T
    Ellaham, S
    Winaver, J
    Hoffman, A
    [J]. PHARMACOLOGY & THERAPEUTICS, 2004, 102 (03) : 223 - 241
  • [2] Changes in brain natriuretic peptide and norepinephrine over time and mortality and morbidity in the Valsartan Heart Failure Trial (Val-HeFT)
    Anand, IS
    Fisher, LD
    Chiang, YT
    Latini, R
    Masson, S
    Maggioni, AP
    Glazer, RD
    Tognoni, G
    Cohn, JN
    [J]. CIRCULATION, 2003, 107 (09) : 1278 - 1283
  • [3] Reference values for N-terminal Pro-B-Type natriuretic peptide in umbilical cord blood
    Bakker, J
    Gies, I
    Slavenburg, B
    Bekers, O
    Delhaas, T
    van Dieijen-Visser, M
    [J]. CLINICAL CHEMISTRY, 2004, 50 (12) : 2465 - 2465
  • [4] N-terminal pro-B-type natriuretic peptide concentrations in mothers just before delivery, in cord blood, and in newborns
    Bar-Oz, B
    Lev-Sagie, A
    Arad, I
    Salpeter, L
    Nir, A
    [J]. CLINICAL CHEMISTRY, 2005, 51 (05) : 926 - 927
  • [5] Prognostic value of plasma N-terminal pro-brain natriuretic peptide in patients with severe sepsis
    Brueckmann, M
    Huhle, G
    Lang, S
    Haase, KK
    Bertsch, T
    Weiss, C
    Kaden, JJ
    Putensen, C
    Borggrefe, M
    Hoffmann, U
    [J]. CIRCULATION, 2005, 112 (04) : 527 - 534
  • [6] Utility of rapid B-type natriuretic peptide assay for diagnosis of symptomatic patent ductus arteriosus in preterm infants
    Choi, BM
    Lee, KH
    Eun, BL
    Yoo, KH
    Hong, YS
    Son, CS
    Lee, JW
    [J]. PEDIATRICS, 2005, 115 (03) : E255 - E261
  • [7] Amino-terminal pro-brain-type natriuretic peptide: Heart or lung disease in pediatric respiratory distress?
    Cohen, S
    Springer, C
    Avital, A
    Perles, Z
    Rein, AJJT
    Argaman, Z
    Nir, A
    [J]. PEDIATRICS, 2005, 115 (05) : 1347 - 1350
  • [8] B-type natriuretic peptide levels in congenital heart disease
    Cowley, CG
    Bradley, JD
    Shaddy, RE
    [J]. PEDIATRIC CARDIOLOGY, 2004, 25 (04) : 336 - 340
  • [9] The use of a bedside assay for plasma B-type natriuretic peptide as a biomarker in the management of patent ductus arteriosus in premature neonates
    Flynn, PA
    Da Graca, RL
    Auld, PAM
    Nesin, M
    Kleinman, CS
    [J]. JOURNAL OF PEDIATRICS, 2005, 147 (01) : 38 - 42
  • [10] Comparison of N-terminal pro-B-type natriuretic peptide levels in critically ill children with sepsis versus acute left ventricular dysfunction
    Fried, Iris
    Bar-Oz, Benjamin
    Algur, Nurit
    Fried, Elchanan
    Gavri, Sagui
    Yatsiv, Ido
    Perles, Zeev
    Rein, Azaria J. J. T.
    Zonis, Zeev
    Bass, Roman
    Nir, Amiram
    [J]. PEDIATRICS, 2006, 118 (04) : E1165 - E1168
123456