Microgravity alters respiratory sinus arrhythmia and short-term heart rate variability in humans

被引:37
作者
Migeotte, PF
Prisk, GK
Paiva, M
机构
[1] Free Univ Brussels, Phys Biol Lab, B-1070 Brussels, Belgium
[2] Univ Calif San Diego, Dept Med, La Jolla, CA 92093 USA
来源
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY | 2003年 / 284卷 / 06期
关键词
heart rate; heart rate variability; respiratory sinus arrhythmia; controlled breathing; microgravity; spaceflight; gravity; autonomic control;
D O I
10.1152/ajpheart.00409.2002
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We studied heart rate (HR), heart rate variability (HRV), and respiratory sinus arrhythmia (RSA) in four male subjects before, during, and after 16 days of spaceflight. The electrocardiogram and respiration were recorded during two periods of 4 min controlled breathing at 7.5 and 15 breaths/min in standing and supine postures on the ground and in microgravity. Low (LF)- and high (HF)-frequency components of the short-term HRV (less than or equal to3 min) were computed through Fourier spectral analysis of the R-R intervals. Early in microgravity, HR was decreased compared with both standing and supine positions and had returned to the supine value by the end of the flight. In microgravity, overall variability, the LF-to-HF ratio, and RSA amplitude and phase were similar to preflight supine values. Immediately postflight, HR increased by similar to15% and remained elevated 15 days after landing. LF/HF was increased, suggesting an increased sympathetic control of HR standing. The overall variability and RSA amplitude in supine decreased postflight, suggesting that vagal tone decreased, which coupled with the decrease in RSA phase shift suggests that this was the result of an adaptation of autonomic control of HR to microgravity. In addition, these alterations persisted for at least 15 days after return to normal gravity (1G).
引用
收藏
页码:H1995 / H2006
页数:12
相关论文
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