Automatic detection of COVID-19 disease using U-Net architecture based fully convolutional network

被引:26
作者
Kalane, Prasad [1 ]
Patil, Sarika [2 ]
Patil, B. P. [3 ]
Sharma, Davinder Pal [4 ]
机构
[1] Anubhuti Res Ctr, Pune, Maharashtra, India
[2] Savitribai Phule Pune Univ, Dept Elect & Telecommun Engn, Sinhgad Coll Engn, Pune, Maharashtra, India
[3] Savitribai Phule Pune Univ, Army Inst Technol, Pune, Maharashtra, India
[4] Univ West Indies, Dept Phys, St Augustine, Trinidad Tobago
关键词
SARS-CoV-2; COVID-19; RT-PCR; U-Net architecture; Deep learning;
D O I
10.1016/j.bspc.2021.102518
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
The severe acute respiratory syndrome coronavirus 2, called a SARS-CoV-2 virus, emerged from China at the end of 2019, has caused a disease named COVID-19, which has now evolved as a pandemic. Amongst the detected Covid-19 cases, several cases are also found asymptomatic. The presently available Reverse Transcription ? Polymerase Chain Reaction (RT-PCR) system for detecting COVID-19 lacks due to limited availability of test kits and relatively low positive symptoms in the early stages of the disease, urging the need for alternative solutions. The tool based on Artificial Intelligence might help the world to develop an additional COVID-19 disease mitigation policy. In this paper, an automated Covid-19 detection system has been proposed, which uses indications from Computer Tomography (CT) images to train the new powered deep learning model- U-Net architecture. The performance of the proposed system has been evaluated using 1000 Chest CT images. The images were obtained from three different sources ? Two different GitHub repository sources and the Italian Society of Medical and Interventional Radiology?s excellent collection. Out of 1000 images, 552 images were of normal persons, and 448 images were obtained from COVID-19 affected people. The proposed algorithm has achieved a sensitivity and specificity of 94.86% and 93.47% respectively, with an overall accuracy of 94.10%. The U-Net architecture used for Chest CT image analysis has been found effective. The proposed method can be used for primary screening of COVID-19 affected persons as an additional tool available to clinicians.
引用
收藏
页数:9
相关论文
共 20 条
[1]  
Ai T, 2019, Radiology, DOI [10.1148/radiol.2020200642, 10.26434/chemrxiv.11860137.v1, DOI 10.1148/RADIOL.2020200642]
[2]   Lung Pattern Classification for Interstitial Lung Diseases Using a Deep Convolutional Neural Network [J].
Anthimopoulos, Marios ;
Christodoulidis, Stergios ;
Ebner, Lukas ;
Christe, Andreas ;
Mougiakakou, Stavroula .
IEEE TRANSACTIONS ON MEDICAL IMAGING, 2016, 35 (05) :1207-1216
[3]   The Lung Image Database Consortium, (LIDC) and Image Database Resource Initiative (IDRI): A Completed Reference Database of Lung Nodules on CT Scans [J].
Armato, Samuel G., III ;
McLennan, Geoffrey ;
Bidaut, Luc ;
McNitt-Gray, Michael F. ;
Meyer, Charles R. ;
Reeves, Anthony P. ;
Zhao, Binsheng ;
Aberle, Denise R. ;
Henschke, Claudia I. ;
Hoffman, Eric A. ;
Kazerooni, Ella A. ;
MacMahon, Heber ;
van Beek, Edwin J. R. ;
Yankelevitz, David ;
Biancardi, Alberto M. ;
Bland, Peyton H. ;
Brown, Matthew S. ;
Engelmann, Roger M. ;
Laderach, Gary E. ;
Max, Daniel ;
Pais, Richard C. ;
Qing, David P-Y ;
Roberts, Rachael Y. ;
Smith, Amanda R. ;
Starkey, Adam ;
Batra, Poonam ;
Caligiuri, Philip ;
Farooqi, Ali ;
Gladish, Gregory W. ;
Jude, C. Matilda ;
Munden, Reginald F. ;
Petkovska, Iva ;
Quint, Leslie E. ;
Schwartz, Lawrence H. ;
Sundaram, Baskaran ;
Dodd, Lori E. ;
Fenimore, Charles ;
Gur, David ;
Petrick, Nicholas ;
Freymann, John ;
Kirby, Justin ;
Hughes, Brian ;
Casteele, Alessi Vande ;
Gupte, Sangeeta ;
Sallam, Maha ;
Heath, Michael D. ;
Kuhn, Michael H. ;
Dharaiya, Ekta ;
Burns, Richard ;
Fryd, David S. .
MEDICAL PHYSICS, 2011, 38 (02) :915-931
[4]   Comparison of Deep Learning Approaches for Multi-Label Chest X-Ray Classification [J].
Baltruschat, Ivo M. ;
Nickisch, Hannes ;
Grass, Michael ;
Knopp, Tobias ;
Saalbach, Axel .
SCIENTIFIC REPORTS, 2019, 9 (1)
[5]  
Barstugan M., 2020, ARXIV PREPRINT ARXIV, DOI 10.4850/arXiv.2003.1105
[6]  
Browning Pd, 2003, ARXIV PREPRINT ARXIV
[7]  
Cohen Joseph Paul, 2020, 11597 ARXIV
[8]   Real-time PCR in clinical microbiology: Applications for a routine laboratory testing [J].
Espy, MJ ;
Uhl, JR ;
Sloan, LM ;
Buckwalter, SP ;
Jones, MF ;
Vetter, EA ;
Yao, JDC ;
Wengenack, NL ;
Rosenblatt, JE ;
Cockerill, FR ;
Smith, TF .
CLINICAL MICROBIOLOGY REVIEWS, 2006, 19 (01) :165-+
[9]  
Huang H, 2020, LANCET, V395, P497, DOI [DOI 10.1016/S0140-6736(20)30183-5, 10.1016/S0140-6736(20)30211-7, DOI 10.1016/S0140-6736(20)30211-7]
[10]   ImageNet Classification with Deep Convolutional Neural Networks [J].
Krizhevsky, Alex ;
Sutskever, Ilya ;
Hinton, Geoffrey E. .
COMMUNICATIONS OF THE ACM, 2017, 60 (06) :84-90