CELL BIOLOGY Ubiquitination without E1 and E2 enzymes

被引:22
作者
Bhogaraju, Sagar [1 ,2 ]
Dikic, Ivan [1 ,2 ]
机构
[1] Goethe Univ Frankfurt, Inst Biochem 2, Sch Med, D-60590 Frankfurt, Germany
[2] Goethe Univ Frankfurt, Buchmann Inst Mol Life Sci, D-60590 Frankfurt, Germany
关键词
LEGIONELLA-PNEUMOPHILA; SYSTEM;
D O I
10.1038/nature17888
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
A protein in the pathogenic bacterium Legionella pneumophila has been found to attach the modifying molecule ubiquitin to human proteins, using a mechanism that, surprisingly, does not involve cellular E1 and E2 enzymes. See Letter p.120
引用
收藏
页码:43 / 44
页数:2
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