CELL BIOLOGY Ubiquitination without E1 and E2 enzymes

被引：24

作者：

Bhogaraju, Sagar ^{[1
,2
]}

Dikic, Ivan ^{[1
,2
]}

机构：

[1] Goethe Univ Frankfurt, Inst Biochem 2, Sch Med, D-60590 Frankfurt, Germany

[2] Goethe Univ Frankfurt, Buchmann Inst Mol Life Sci, D-60590 Frankfurt, Germany

来源：

NATURE | 2016年 / 533卷 / 7601期

关键词：

LEGIONELLA-PNEUMOPHILA; SYSTEM;

D O I：

10.1038/nature17888

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A protein in the pathogenic bacterium Legionella pneumophila has been found to attach the modifying molecule ubiquitin to human proteins, using a mechanism that, surprisingly, does not involve cellular E1 and E2 enzymes. See Letter p.120

引用

页码：43 / 44

页数：2

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