Surgery for cervical cancer: consensus & controversies

被引:38
作者
Poddar, Pabashi [1 ]
Maheshwari, Amita [1 ,2 ]
机构
[1] Homi Bhabha Natl Inst, Tata Mem Ctr, Div Gynecol Oncol, Mumbai, Maharashtra, India
[2] Tata Mem Hosp, Homi Bhabha Natl Inst, Div Gynecol Oncol, Dr Ernest Borges Rd,Parel, Mumbai 400 012, Maharashtra, India
关键词
Early-stage cervical cancer; fertility preservation; minimal invasive surgery; neoadjuvant chemotherapy; ovarian preservation; radical surgery; SPARING RADICAL HYSTERECTOMY; NEOADJUVANT CHEMOTHERAPY; OVARIAN METASTASES; PELVIC LYMPHADENECTOMY; STAGE IB2; MANAGEMENT; MULTICENTER; CARCINOMA; TRACHELECTOMY; FERTILITY;
D O I
10.4103/ijmr.IJMR_4240_20
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Surgery plays an important role in the management of early-stage cervical cancer. Type III radical hysterectomy with bilateral pelvic lymph node dissection using open route is the standard surgical procedure. There is level I evidence against the use of laparoscopic/robotic approach for radical hysterectomy for cervical cancer. Emerging data support the use of sentinel lymph node biopsy and nerve sparing radical hysterectomy in carefully selected patients with early-stage disease. In locally advanced cervical cancer patients, the use of neoadjuvant chemotherapy (NACT) followed by radical surgery yields inferior disease-free survival compared to definitive concurrent chemoradiation therapy. Therefore, definitive concurrent chemoradiation is the standard treatment for locally advanced disease. Fertility preserving surgery is feasible in highly selected young patients. Role of less-radical surgical procedures in patients' with low-stage disease with good prognostic factors is under evaluation.
引用
收藏
页码:284 / 292
页数:9
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