Synthesis of α,ω-bis(oxazolidinone)polyoxyethylene via a lithium bromide-catalyzed reaction of oligoethylene glycol diglycidyl ethers with isocyanates

被引：22

作者：

Aroua, Lotfi ^{[1
]}

Baklouti, Ahmed ^{[1
]}

机构：

[1] Fac Sci Tunis, Dept Chem, Lab Struct Organ Chem, Tunis 2092, Tunisia

来源：

SYNTHETIC COMMUNICATIONS | 2007年 / 37卷 / 11期

关键词：

diglycidyl ethers; isocynates; lithium bromide; oligoethylene glycols; oxazolidinone;

D O I：

10.1080/00397910701316920

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of bis(oxazolidinone) polyoxyethylene derivatives 2a - h from oligoethylene glycols diglycidyl ethers 1a - e and isocyanates is reported. The reaction was achieved by lithium bromide and tributylphosphine oxide. These bis-oxazolidinones may have important antibacterial activity.

引用

页码：1935 / 1942

页数：8

共 43 条

[1] CHIRAL OXAZOLIDINONES FROM N-BOC DERIVATIVES OF BETA-AMINO ALCOHOLS - EFFECT OF A N-METHYL SUBSTITUENT ON REACTIVITY AND STEREOSELECTIVITY [J].

AGAMI, C ;

COUTY, F ;

HAMON, L ;

VENIER, O .

TETRAHEDRON LETTERS, 1993, 34 (28) :4509-4512

[2]

Ager DJ, 1997, ALDRICHIM ACTA, V30, P3

[3]

AGER DJ, 1996, ALDRICHIM ACTA, V96, P835

[4]

Ammazzalorso Alessandra, 2004, Farmaco (Lausanne), V59, P685, DOI 10.1016/j.farmac.2004.05.002

[5]

AMORA V, 2004, BIOORG MED CHEM LETT, V14, P4647

[6]

[Anonymous], [No title captured]

[7] Synthesis of bis(β-fluorothiocyanato)polyoxyethylene glycols [J].

Aroua, L ;

Hedhli, A ;

Baklouti, A .

JOURNAL OF FLUORINE CHEMISTRY, 2000, 105 (01) :7-9

[8] Synthesis of bis(vicinal difluorinated) polyoxyethylene glycols [J].

Aroua, L ;

Hedhli, A ;

Baklouti, A .

SYNTHETIC COMMUNICATIONS, 2000, 30 (15) :2807-2812

[9]

AROVA L, 1999, SYNTHESIS-STUTTGART, P85

[10] UNUSUAL CYCLOADDITION OF OXIRANES WITH ISOCYANATES CATALYZED BY TETRAPHENYLSTIBONIUM IODIDE - SELECTIVE FORMATION OF 3,4-DISUBSTITUTED OXAZOLIDINONES [J].

BABA, A ;

FUJIWARA, M ;

MATSUDA, H .

TETRAHEDRON LETTERS, 1986, 27 (01) :77-80

← 1 2 3 4 5 →