Assessing computational genomics skills: Our experience in the H3ABioNet African bioinformatics network

被引：9

作者：

Jongeneel, C. Victor ^{[1
,2
,3
]}

Achinike-Oduaran, Ovokeraye ^{[4
]}

Adebiyi, Ezekiel ^{[5
,6
]}

Adebiyi, Marion ^{[5
,6
]}

Adeyemi, Seun ^{[6
,7
]}

Akanle, Bola ^{[6
,7
]}

Aron, Shaun ^{[4
]}

Ashano, Efejiro ^{[6
,8
]}

Bendou, Hocine ^{[9
]}

Botha, Gerrit ^{[9
]}

Chimusa, Emile ^{[9
,10
]}

Choudhury, Ananyo ^{[4
]}

Donthu, Ravikiran ^{[1
]}

Drnevich, Jenny ^{[1
]}

Falola, Oluwadamila ^{[6
]}

Fields, Christopher J. ^{[1
]}

Hazelhurst, Scott ^{[4
,11
]}

Hendry, Liesl ^{[4
]}

Isewon, Itunuoluwa ^{[5
,6
]}

Khetani, Radhika S. ^{[1
,14
]}

Kumuthini, Judit ^{[10
]}

Kimuda, Magambo Phillip ^{[12
]}

Magosi, Lerato ^{[13
,15
]}

Mainzer, Liudmila Sergeevna ^{[1
,2
,3
]}

Maslamoney, Suresh ^{[9
]}

Mbiyavanga, Mamana ^{[9
,10
]}

Meintjes, Ayton ^{[9
]}

Mugutso, Danny ^{[9
]}

Mpangase, Phelelani ^{[4
]}

Munthali, Richard ^{[4
]}

Nembaware, Victoria ^{[9
]}

Ndhlovu, Andrew ^{[4
]}

Odia, Trust ^{[6
]}

Okafor, Adaobi ^{[6
]}

Oladipo, Olaleye ^{[6
,7
]}

Panji, Sumir ^{[9
]}

Pillay, Venesa ^{[4
]}

Rendon, Gloria ^{[1
,2
,3
]}

Sengupta, Dhriti ^{[4
]}

Mulder, Nicola ^{[9
]}

机构：

[1] Univ Illinois, Roy J Carver Biotechnol Ctr, High Performance Biol Comp, Urbana, IL 61801 USA

[2] Univ Illinois, Inst Genom Biol, Urbana, IL 61801 USA

[3] Univ Illinois, Natl Ctr Supercomp Applicat, Urbana, IL 61801 USA

[4] Univ Witwatersrand, Sydney Brenner Inst Mol Biosci, Johannesburg, South Africa

[5] Covenant Univ, Dept Comp & Informat Sci, Ota, Nigeria

[6] Covenant Univ, Covenant Univ Bioinformat Res CUBRe, Ota, Nigeria

[7] Covenant Univ, Ctr Syst & Informat Serv, Ota, Nigeria

[8] FMST, Natl Biotechnol Dev Agcy NABDA, Abuja, Nigeria

[9] Univ Cape Town, Inst Infect Dis & Mol Med, Dept Integrat Biomed Sci, Computat Biol Div, Rondebosch, South Africa

[10] Ctr Prote & Genom Res, Cape Town, South Africa

[11] Univ Witwatersrand, Sch Elect & Informat Engn, Johannesburg, South Africa

[12] Rhodes Univ, Dept Biochem & Microbiol, Res Unit Bioinformat RUBi, Grahamstown, South Africa

[13] Botswana Harvard AIDS Inst Partnership, Gaborone, Botswana

[14] Harvard TH Chan Sch Publ Hlth, Boston, MA USA

[15] Univ Oxford, Oxford, England

来源：

PLOS COMPUTATIONAL BIOLOGY | 2017年 / 13卷 / 06期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1371/journal.pcbi.1005419

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The H3ABioNet pan-African bioinformatics network, which is funded to support the Human Heredity and Health in Africa (H3Africa)program, has developed node-assessment exercises to gauge the ability of its participating research and service groups to analyze typical genome-wide datasets being generated by H3Africa research groups. We describe a framework for the assessment of computational genomics analysis skills, which includes standard operating procedures, training and test datasets, and a process for administering the exercise. We present the experiences of 3 research groups that have taken the exercise and the impact on their ability to manage complex projects. Finally, we discuss the reasons why many H3ABioNet nodes have declined so far to participate and potential strategies to encourage them to do so.

引用

页数：10

共 3 条

[1] "Broadband" Bioinformatics Skills Transfer with the Knowledge Transfer Programme (KTP): Educational Model for Upliftment and Sustainable Development
Chimusa, Emile R.
Mbiyavanga, Mamana
Masilela, Velaphi
Kumuthini, Judit
[J]. PLOS COMPUTATIONAL BIOLOGY, 2015, 11 (11)
[2] H3ABioNet, a sustainable pan-African bioinformatics network for human heredity and health in Africa
Mulder, Nicola J.
Adebiyi, Ezekiel
Alami, Raouf
Benkahla, Alia
Brandful, James
Doumbia, Seydou
Everett, Dean
Fadlelmola, Faisal M.
Gaboun, Fatima
Gaseitsiwe, Simani
Ghazal, Hassan
Hazelhurst, Scott
Hide, Winston
Ibrahimi, Azeddine
Fakim, Yasmina Jaufeerally
Jongeneel, C. Victor
Joubert, Fourie
Kassim, Samar
Kayondo, Jonathan
Kumuthini, Judit
Lyantagaye, Sylvester
Makani, Julie
Alzohairy, Ahmed Mansour
Masiga, Daniel
Moussa, Ahmed
Nash, Oyekanmi
Oukem-Boyer, Odile Ouwe Missi
Owusu-Dabo, Ellis
Panji, Sumir
Patterton, Hugh
Radouani, Fouzia
Sadki, Khalid
Seghrouchni, Fouad
Bishop, Ozlem Tastan
Tiffin, Nicki
Ulenga, Nzovu
[J]. GENOME RESEARCH, 2016, 26 (02) : 271 - 277
[3] Enabling the genomic revolution in Africa
Rotimi, Charles
[J]. SCIENCE, 2014, 344 (6190) : 1346 - 1348

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