Production of bioproducts by endophytic fungi: chemical ecology, biotechnological applications, bottlenecks, and solutions

被引：60

作者：

Yan, Lu ^{[1
]}

Zhao, Haobin ^{[1
]}

Zhao, Xixi ^{[1
]}

Xu, Xiaoguang ^{[1
]}

Di, Yichao ^{[1
]}

Jiang, Chunmei ^{[1
]}

Shi, Junling ^{[1
]}

Shao, Dongyan ^{[1
]}

Huang, Qingsheng ^{[1
]}

Yang, Hui ^{[1
]}

Jin, Mingliang ^{[1
]}

机构：

[1] Northwestern Polytech Univ, Sch Life Sci, Key Lab Space Biosci & Biotechnol, 127 Youyi West Rd, Xian 710072, Shaanxi, Peoples R China

来源：

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY | 2018年 / 102卷 / 15期

基金：

中国国家自然科学基金;

关键词：

Endophyte; Mutualism; Interaction benefit; Adversity tolerance; Nutrient acquisition; Biocontrol; Bioproduct; SILVER NANOPARTICLES; PLANT-GROWTH; IN-VITRO; STRUCTURAL ELUCIDATION; EXOPOLYSACCHARIDE PRODUCTION; MEDICINAL-PLANT; SALT TOLERANCE; DOWNY MILDEW; HOST-PLANT; ANTIOXIDANT;

D O I：

10.1007/s00253-018-9101-7

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Endophytes are microorganisms that colonize the interior of host plants without causing apparent disease. They have been widely studied for their ability to modulate relationships between plants and biotic/abiotic stresses, often producing valuable secondary metabolites that can affect host physiology. Owing to the advantages of microbial fermentation over plant/cell cultivation and chemical synthesis, endophytic fungi have received significant attention as a mean for secondary metabolite production. This article summarizes currently reported results on plant-endophyte interaction hypotheses and highlights the biotechnological applications of endophytic fungi and their metabolites in agriculture, environment, biomedicine, energy, and biocatalysts. Current bottlenecks in industrial development and commercial applications as well as possible solutions are also discussed.

引用

页码：6279 / 6298

页数：20

共 156 条

[11] Endophytic Insect-Parasitic Fungi Translocate Nitrogen Directly from Insects to Plants [J].

Behie, S. W. ;

Zelisko, P. M. ;

Bidochka, M. J. .

SCIENCE, 2012, 336 (6088) :1576-1577

[12] Nutrient transfer in plant-fungal symbioses [J].

Behie, Scott W. ;

Bidochka, Michael J. .

TRENDS IN PLANT SCIENCE, 2014, 19 (11) :734-740

[13] Ubiquity of Insect-Derived Nitrogen Transfer to Plants by Endophytic Insect-Pathogenic Fungi: an Additional Branch of the Soil Nitrogen Cycle [J].

Behie, Scott W. ;

Bidochka, Michael J. .

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2014, 80 (05) :1553-1560

[14] Metabolite induction via microorganism co-culture: A potential way to enhance chemical diversity for drug discovery [J].

Bertrand, Samuel ;

Bohni, Nadine ;

Schnee, Sylvain ;

Schumpp, Olivier ;

Gindro, Katia ;

Wolfender, Jean-Luc .

BIOTECHNOLOGY ADVANCES, 2014, 32 (06) :1180-1204

[15] Solid state fermentation of soybean waste and an up-flow column bioreactor for continuous production of camptothecine by an endophytic fungus Fusarium oxysporum [J].

Bhalkar, Bhumika N. ;

Bedekar, Priyanka A. ;

Kshirsagar, Siddheshwar D. ;

Govindwar, Sanjay P. .

RSC ADVANCES, 2016, 6 (61) :56527-56536

[16] Camptothecine production by mixed fermentation of two endophytic fungi from Nothapodytes nimmoniana [J].

Bhalkar, Bhumika N. ;

Patil, Swapnil M. ;

Govindwar, Sanjay P. .

FUNGAL BIOLOGY, 2016, 120 (6-7) :873-883

[17] Production of taxadiene by engineering of mevalonate pathway in Escherichia coli and endophytic fungus Alternaria alternata TPF6 [J].

Bian, Guangkai ;

Yuan, Yujie ;

Tao, Hui ;

Shi, Xiaofei ;

Zhong, Xiaofang ;

Han, Yichao ;

Fu, Shuai ;

Fang, Chengxiang ;

Deng, Zixin ;

Liu, Tiangang .

BIOTECHNOLOGY JOURNAL, 2017, 12 (04)

[18] ADAPTATIONS TO ENVIRONMENTAL STRESSES [J].

BOHNERT, HJ ;

NELSON, DE ;

JENSEN, RG .

PLANT CELL, 1995, 7 (07) :1099-1111

[19] Bioactive metabolites from an endophytic fungus of Aspergillus species isolated from seeds of Gloriosa superba Linn. [J].

Budhiraja, Abhishek ;

Nepali, Kunal ;

Sapra, Sameer ;

Gupta, Suruchi ;

Kumar, Sanjay ;

Dhar, K. L. .

MEDICINAL CHEMISTRY RESEARCH, 2013, 22 (01) :323-329

[20] FUNGAL ENDOPHYTES IN STEMS AND LEAVES - FROM LATENT PATHOGEN TO MUTUALISTIC SYMBIONT [J].

CARROLL, G .

ECOLOGY, 1988, 69 (01) :2-9

← 1 2 3 4 5 6 7 8 9 10 →