Convenient and Direct Azidation of sec-Benzyl Alcohols by Trimethylsilyl Azide with Bismuth(III) Triflate Catalyst

被引：12

作者：

Tummatorn, Jumreang ^{[1
,2
]}

Thongsornkleeb, Charnsak ^{[1
,2
]}

Ruchirawat, Somsak ^{[1
,2
]}

Thongaram, Phanida ^{[1
]}

Kaewmee, Benyapa ^{[1
]}

机构：

[1] Chulabhorn Res Inst, Med Chem Lab, Bangkok 10210, Thailand

[2] Minist Educ, Ctr Excellence Environm Hlth & Toxicol EHT, Chulabhorn Grad Inst, Program Chem Biol, Bangkok 10210, Thailand

来源：

SYNTHESIS-STUTTGART | 2015年 / 47卷 / 03期

关键词：

azides; catalysis; bismuth; alcohols; MEDIATED ELECTROPHILIC CYCLIZATION; ARYLMETHYL AZIDES; DIRECT CONVERSION; ALKYL AZIDES; ISOQUINOLINES; REDUCTION; SCHMIDT; ETHERS; ACIDS; MILD;

D O I：

10.1055/s-0034-1379967

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

sec-Benzyl azides were efficiently prepared by bismuth(III)-catalyzed direct azidation of sec-benzyl alcohols. The reaction was applied to a variety of substrates to provide the desired products in up to 99% yield within a short reaction time.

引用

页码：323 / 329

页数：7

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