RORγt inhibitors suppress TH17 responses in inflammatory arthritis and inflammatory bowel disease

被引：30

作者：

de Wit, Jelle ^{[1
]}

Al-Mossawi, M. Hussein ^{[1
]}

Huehn, Michael H. ^{[2
]}

Arancibia-Carcamo, Carolina V. ^{[2
]}

Doig, Karen ^{[1
]}

Kendrick, Benjamin ^{[1
]}

Gundle, Roger ^{[1
]}

Taylor, Peter ^{[3
]}

Mcclanahan, Terri ^{[4
]}

Murphy, Erin ^{[4
]}

Zhang, Hongjun ^{[5
]}

Barr, Ken ^{[5
]}

Miller, J. Richard ^{[5
]}

Hu, Xiao ^{[5
]}

Aicher, Thomas D. ^{[6
]}

Morgan, Rodney W. ^{[6
]}

Glick, Gary D. ^{[7
]}

Zaller, Dennis ^{[5
]}

Correll, Craig ^{[5
]}

Powrie, Fiona ^{[2
,8
]}

Bowness, Paul ^{[1
,3
]}

机构：

[1] Univ Oxford, Nuffield Dept Orthopaed Rheumatol & Musculoskelet, Oxford, England

[2] Univ Oxford, John Radcliffe Hosp, Nuffield Dept Clin Med, Translat Gastroenterol Unit,Expt Med Div, Oxford OX3 9DU, England

[3] Univ Oxford, Nuffield Orthopaed Ctr, Natl Inst Hlth Res, Musculoskeletal Biomed Res Unit, Oxford, England

[4] Merck Res Labs, Palo Alto, CA USA

[5] Merck Res Labs, Boston, MA USA

[6] Lycera Corp, Ann Arbor, MI USA

[7] Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA

[8] Univ Oxford, Kennedy Inst Rheumatol, Nuffield Dept Orthopaed Rheumatol & Musculoskelet, Oxford, England

来源：

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY | 2016年 / 137卷 / 03期

基金：

英国医学研究理事会; 英国惠康基金;

关键词：

EXPRESSION; RECEPTOR; CELLS; DIFFERENTIATION;

D O I：

10.1016/j.jaci.2015.09.048

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

[No abstract available]

引用

页码：960 / 963

页数：12

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