Transition-Metal-Catalyzed Direct Arylation of (Hetero)Arenes by C-H Bond Cleavage

被引：2511
作者：
Ackermann, Lutz [1 ]
Vicente, Ruben [1 ]
Kapdi, Anant R. [1 ]
机构：
[1] Univ Gottingen, Inst Organ & Biomol Chem, D-37077 Gottingen, Germany
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2009年 / 48卷 / 52期
关键词：
arylation; biaryls; C-H functionalization; homogeneous catalysis; transition metals; CROSS-COUPLING REACTIONS; INTRAMOLECULAR DIRECT ARYLATION; DIRECT C-2 ARYLATION; INCLUDING FREE (NH)-IMIDAZOLE; PROTON-ABSTRACTION MECHANISM; PALLADIUM-PROMOTED SYNTHESIS; MEDIATED DIRECT ARYLATION; ONE-POT SYNTHESIS; ARYL CHLORIDES; REGIOSELECTIVE ARYLATION;
D O I：
10.1002/anie.200902996
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
(figure represented) Cutting across: Direct arylations are increasingly viable alternatives to conventional cross-coupling reactions with stoichiometric amounts of organometallic reagents (see Scheme). This Review summarizes recent progress in the rapidly evolving research area of transition-metalcatalyzed C-H bond-cleavage reactions for (hetero)aryl syntheses. © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码：9792 / 9826
页数：35
相关论文
共 414 条
[1]   Catalytic arylation reactions by C-H bond activation with aryl tosylates [J].
Ackermann, L ;
Althammer, A ;
Born, R .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2006, 45 (16) :2619-2622
[2]   Air-stable phosphine oxides as preligands for catalytic activation reactions of C-Cl, C-F, and C-H bonds [J].
Ackermann, L ;
Born, R ;
Spatz, JH ;
Althammer, A ;
Gschrei, CJ .
PURE AND APPLIED CHEMISTRY, 2006, 78 (02) :209-214
[3]   Cross-coupling reactions of aryl and vinyl chlorides catalyzed by a palladium complex derived from an air-stable H-phosphonate [J].
Ackermann, L ;
Gschrei, CJ ;
Althammer, A ;
Riederer, M .
CHEMICAL COMMUNICATIONS, 2006, (13) :1419-1421
[4]   Efficient aryl-(hetero)aryl coupling by activation of C-Cl and C-F bonds using nickel complexes of air-stable phosphine oxides [J].
Ackermann, L ;
Born, R ;
Spatz, JH ;
Meyer, D .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2005, 44 (44) :7216-7219
[5]  
Ackermann L, 2009, MODERN ARYLATION METHODS, P1
[6]   Phosphine oxides as preligands in ruthenium-catalyzed arylations via C-H bond functionalization using aryl chlorides [J].
Ackermann, L .
ORGANIC LETTERS, 2005, 7 (14) :3123-3125
[7]   Modular diamino- and dioxophosphine oxides and chlorides as ligands for transition-metal-catalyzed C-C and C-N couplings with aryl chlorides [J].
Ackermann, L ;
Born, R .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2005, 44 (16) :2444-2447
[8]  
Ackermann L., 2007, ANGEW CHEM, V119, P6482
[9]  
Ackermann L., 2005, Angew. Chem, V117, P2497
[10]  
Ackermann L., 2006, Angew. Chem, V118, P7789
12345678910