Characterization of a small mobilizable transposon, MTnSag1, in Streptococcus agalactiae

被引:23
作者
Achard, Adeline
Leclercq, Roland
机构
[1] Univ Caen, Microbiol Serv, F-14033 Caen, France
[2] Univ Caen, EA Interact Hote & Microorganismes Epitheliums, CHU Cote Nacre, F-14033 Caen, France
关键词
D O I
10.1128/JB.00213-07
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The transposon MTnSag1 from Streptococcus agalactiae carried an IS1-like transposase gene and the lnu(C) gene, which encoded a lincosamide nucleotidyltransferase. MTnSag1 could be mobilized by the conjugative transposon Tn916. An intermediate circular form of MTnSag1 and a putative origin of transfer at the 3' end of the Inu(C) gene were characterized.
引用
收藏
页码:4328 / 4331
页数:4
相关论文
共 17 条
  • [1] New lnu(C) gene conferring resistance to lincomycin by nucleotidylation in Streptococcus agalactiae UCN36
    Achard, A
    Villers, C
    Pichereau, V
    Leclercq, R
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2005, 49 (07) : 2716 - 2719
  • [2] The clostridial mobilisable transposons
    Adams, V
    Lyras, D
    Farrow, KA
    Rood, JI
    [J]. CELLULAR AND MOLECULAR LIFE SCIENCES, 2002, 59 (12) : 2033 - 2043
  • [3] Functional domains of the IS1 transposase:: analysis in vivo and in vitro
    Bao, TH
    Turlan, C
    Chandler, M
    [J]. MOLECULAR MICROBIOLOGY, 2004, 53 (05) : 1529 - 1543
  • [4] Circularization of Tn916 is required for expression of the transposon-encoded transfer functions:: characterization of long tetracycline-inducible transcripts reading through the attachment site
    Celli, J
    Trieu-Cuot, P
    [J]. MOLECULAR MICROBIOLOGY, 1998, 28 (01) : 103 - 117
  • [5] Group B streptococcal disease in nonpregnant adults
    Farley, MM
    [J]. CLINICAL INFECTIOUS DISEASES, 2001, 33 (04) : 556 - 561
  • [6] Genomic analysis of the erythromycin resistance element Tn5398 from Clostridium difficile
    Farrow, KA
    Lyras, D
    Rood, JI
    [J]. MICROBIOLOGY-SGM, 2001, 147 : 2717 - 2728
  • [7] Specific binding of integrase to the origin of transfer (oriT) of the conjugative transposon Tn916
    Hinerfeld, D
    Churchward, G
    [J]. JOURNAL OF BACTERIOLOGY, 2001, 183 (09) : 2947 - 2951
  • [8] A FUNCTIONAL ORIGIN OF TRANSFER (ORIT) ON THE CONJUGATIVE TRANSPOSON TN916
    JAWORSKI, DD
    CLEWELL, DB
    [J]. JOURNAL OF BACTERIOLOGY, 1995, 177 (22) : 6644 - 6651
  • [9] Insertion sequences
    Mahillon, J
    Chandler, M
    [J]. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS, 1998, 62 (03) : 725 - +
  • [10] Genetic basis of antibiotic resistance in Streptococcus agalactiae strains isolated in a French hospital
    Poyart, C
    Jardy, L
    Quesne, G
    Berche, P
    Trieu-Cuot, P
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2003, 47 (02) : 794 - 797