Dual doped biocompatible multicolor luminescent carbon dots for bio labeling, UV-active marker and fluorescent polymer composite

被引:59
作者
Das, Poushali [1 ]
Ganguly, Sayan [2 ]
Mondal, Subhadip [2 ]
Ghorai, Uttam Kumar [3 ]
Maity, Priti Prasanna [4 ]
Choudhary, Sumita [5 ]
Gangopadhyay, Subhashis [5 ]
Dhara, Santanu [4 ]
Banerjee, Susanta [6 ]
Das, Narayan Ch. [1 ,2 ]
机构
[1] Indian Inst Technol, Sch Nanosci & Technol, Kharagpur, W Bengal, India
[2] Indian Inst Technol, Ctr Rubber Technol, Kharagpur 721302, W Bengal, India
[3] Ramakrishna Mission Vidyamandira, Swami Vivekananda Res Ctr, Dept Ind Chem & Appl Chem, Belur Math, Howrah, India
[4] Indian Inst Technol, Sch Med Sci & Technol, Kharagpur, W Bengal, India
[5] Birla Inst Technol & Sci, Dept Phys, Pilani, Rajasthan, India
[6] Indian Inst Technol, Ctr Mat Sci, Kharagpur, W Bengal, India
关键词
carbon dots; cell labeling; fluorescence; fluorescent polymer composite; UV-active marker; ONE-STEP SYNTHESIS; HIGH QUANTUM YIELD; GREEN SYNTHESIS; SELECTIVE DETECTION; NANOPARTICLE SYNTHESIS; SENSITIVE DETECTION; FACILE SYNTHESIS; NITROGEN; NANODOTS; CELLS;
D O I
10.1002/bio.3520
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
We report on metal-non-metal doped carbon dots with very high photoluminescent properties in solution. Magnesium doping to tamarind extract associated with nitrogen-doping is for the first time reported here which also produce very high quantum yield. Our aim is to develop such dual doped carbon dots which can also serve living cell imaging with easy permeation towards cells and show non-cytotoxic attributes. More importantly, the chemical signatures of the carbon dots unveiled in this work can support their easy solubilization into water; even in sub-ambient temperature. The cytotoxicity assay proves the almost negligible cytotoxic effect against human cell lines. Moreover, the use of carbon dots in UV-active marker and polymer composites are also performed which gave clear distinguishable features of fluorescent nanoparticles. Hitherto, the carbon dots can be commercially prepared without adopting any rigorous methods and also can be used as non-photo-bleachable biomarkers of living cells.
引用
收藏
页码:1136 / 1145
页数:10
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