Two Cases of False-Positive Dengue Non-Structural Protein 1 (NS1) Antigen in Patients with Hematological Malignancies and a Review of the Literature on the Use of NS1 for the Detection of Dengue Infection

被引：21

作者：

Chung, Shimin J.

Krishnan, Prabha U.

Leo, Yee Sin

机构：

[1] Singapore Gen Hosp, Dept Infect Dis, Singapore, Singapore

[2] Tan Tock Seng Hosp, Dept Lab Med, Singapore, Singapore

[3] Minist Hlth, Natl Publ Hlth Lab, Singapore, Singapore

[4] Tock Seng Hosp, Inst Infect Dis & Epidemiol, Communicable Dis Ctr, Singapore, Singapore

[5] Natl Univ Singapore, Yong Loo Lin Sch Med, Singapore 117595, Singapore

[6] Nanyang Technol Univ, Lee Kong Chian Sch Med, Singapore 639798, Singapore

来源：

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE | 2015年 / 92卷 / 02期

关键词：

EARLY-DIAGNOSIS; RT-PCR; VIRUS; TESTS; ASSAY; SENSITIVITY; ACCURACY; BRAZIL; KIT;

D O I：

10.4269/ajtmh.14-0247

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Early diagnosis of dengue has been made easier in recent years owing to the advancement in diagnostic technologies. The rapid non-structural protein 1 (NS1) test strip is widely used in many developed and developing regions at risk of dengue. Despite the relatively high specificity of this test, we recently encountered two cases of false-positive dengue NS1 antigen in patients with underlying hematological malignancies. We reviewed the literature for causes of false-positive dengue NS1.

引用

页码：367 / 369

页数：3

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