Congenital Cutaneous Candidiasis With Systemic Dissemination in a Preterm Infant

被引:4
作者
Miras, Isabel [1 ]
Vierge, Eva [2 ]
Garcia, Macarena [3 ]
Arruza, Luis [4 ]
Criado, Enrique [5 ]
Ramos, Jose Tomas [6 ]
Martinez-Orgado, Jose [7 ]
机构
[1] Hosp Univ Guadalajara, Dept Pediat & Neonatol, Calle Donantes Sangre Sn, Guadalajara 19002, Spain
[2] Hosp Clin San Carlos IdISSC, Inst Nino & Adolescente, Div Neonatol, Madrid, Spain
[3] Hosp Infanta Cristina, Dept Pediat & Neonatol, Parla, Spain
[4] Hosp Clin San Carlos, Dept Neonatol, Madrid, Spain
[5] Hosp Clin San Carlos, Dept Neonatol, Madrid, Spain
[6] Univ Complutense Madrid, Hosp Clin San Carlos, Dept Pediat, Madrid, Spain
[7] Univ Complutense Madrid, Hosp Clin San Carlos, Dept Neoantol, Madrid, Spain
关键词
infectious disease; fungal infection; Candida albicans; neonates; extremely low birth weight; LIPOSOMAL AMPHOTERICIN-B; BIRTH-WEIGHT INFANTS; NEONATAL CANDIDIASIS; RISK-FACTORS; INVASIVE CANDIDIASIS; MANAGEMENT; OUTCOMES; INFECTIONS; THERAPY; EPIDEMIOLOGY;
D O I
10.1097/INF.0000000000003080
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Congenital cutaneous candidiasis is an infrequent invasive fungal infection that usually appears in the first days of life. Extremely low birth weight infants are the most frequently affected. Classic presentation includes diffuse extensive erythematous rash with papules, plaques, pustules and vesicles, which later undergoes desquamation. Systemic dissemination is common in extremely low birth weight infants. Blood, urine and cerebrospinal fluid evaluation should be included in the initial assessment. Early and prolonged treatment has been associated with decreased mortality. We report the case of congenital cutaneous candidiasis in a preterm infant. Early skin lesion recognition allowed establishing adequate treatment in the first hours of life.
引用
收藏
页码:E230 / E233
页数:4
相关论文
共 25 条
  • [1] Vulvovaginal Candidiasis in Pregnancy
    Aguin, T. J.
    Sobel, J. D.
    [J]. CURRENT INFECTIOUS DISEASE REPORTS, 2015, 17 (06)
  • [2] Neonatal Candidiasis: Epidemiology, Risk Factors, and Clinical Judgment
    Benjamin, Daniel K., Jr.
    Stoll, Barbara J.
    Gantz, Marie G.
    Walsh, Michele C.
    Sanchez, Pablo J.
    Das, Abhik
    Shankaran, Seetha
    Higgins, Rosemary D.
    Auten, Kathy J.
    Miller, Nancy A.
    Walsh, Thomas J.
    Laptook, Abbot R.
    Carlo, Waldemar A.
    Kennedy, Kathleen A.
    Finer, Neil N.
    Duara, Shahnaz
    Schibler, Kurt
    Chapman, Rachel L.
    Van Meurs, Krisa P.
    Frantz, Ivan D., III
    Phelps, Dale L.
    Poindexter, Brenda B.
    Bell, Edward F.
    O'Shea, T. Michael
    Watterberg, Kristi L.
    Goldberg, Ronald N.
    [J]. PEDIATRICS, 2010, 126 (04) : E865 - E873
  • [3] Neonatal candidiasis among extremely low birth weight infants: Risk factors, mortality rates, and neurodevelopmental outcomes at 18 to 22 months
    Benjamin, DK
    Stoll, BJ
    Fanaroff, AA
    McDonald, SA
    Oh, W
    Higgins, RD
    Duara, S
    Poole, K
    Laptook, A
    Goldberg, R
    [J]. PEDIATRICS, 2006, 117 (01) : 84 - 92
  • [4] Congenital Systemic Fungus Infection in Twin Prematurity-A Case Report and Literature Review
    Chen, Wei-Yu
    Chen, Shu-Jen
    Tsai, Shu-Fan
    Tsao, Pei-Chen
    Tang, Ren-Bin
    Soong, Wen-Jun
    [J]. AJP REPORTS, 2015, 5 (01): : E46 - E50
  • [5] Nail dystrophy in congenital cutaneous candidiasis
    Clegg, HW
    Prose, NS
    Greenberg, DN
    [J]. PEDIATRIC DERMATOLOGY, 2003, 20 (04) : 342 - 344
  • [6] Congenital cutaneous candidiasis: Clinical presentation, pathogenesis, and management guidelines
    Darmstadt, GL
    Dinulos, JG
    Miller, Z
    [J]. PEDIATRICS, 2000, 105 (02) : 438 - 444
  • [7] Fluconazole Prophylaxis for the Prevention of Candidiasis in Premature Infants: A Meta-analysis Using Patient-level Data
    Ericson, Jessica E.
    Kaufman, David A.
    Kicklighter, Stephen D.
    Bhatia, Jatinder
    Testoni, Daniela
    Gao, Jamie
    Smith, P. Brian
    Prather, Kristi O.
    Benjamin, Daniel K., Jr.
    [J]. CLINICAL INFECTIOUS DISEASES, 2016, 63 (05) : 604 - 610
  • [8] Filioti J, 2007, INTENS CARE MED, V33, P1272, DOI 10.1007/s00134-007-0672-5
  • [9] Empiric Antifungal Therapy and Outcomes in Extremely Low Birth Weight Infants with Invasive Candidiasis
    Greenberg, Rachel G.
    Benjamin, Daniel K., Jr.
    Gantz, Marie G.
    Cotten, C. Michael
    Stoll, Barbara J.
    Walsh, Michele C.
    Sanchez, Pablo J.
    Shankaran, Seetha
    Das, Abhik
    Higgins, Rosemary D.
    Miller, Nancy A.
    Auten, Kathy J.
    Walsh, Thomas J.
    Laptook, Abbot R.
    Carlo, Waldemar A.
    Kennedy, Kathleen A.
    Finer, Neil N.
    Duara, Shahnaz
    Schibler, Kurt
    Ehrenkranz, Richard A.
    Van Meurs, Krisa P.
    Frantz, Ivan D., III
    Phelps, Dale L.
    Poindexter, Brenda B.
    Bell, Edward F.
    O'Shea, T. Michael
    Watterberg, Kristi L.
    Goldberg, Ronald N.
    Smith, P. Brian
    [J]. JOURNAL OF PEDIATRICS, 2012, 161 (02) : 264 - +
  • [10] ESCMID* guideline for the diagnosis and management of Candida diseases 2012: prevention and management of invasive infections in neonates and children caused by Candida spp.
    Hope, W. W.
    Castagnola, E.
    Groll, A. H.
    Roilides, E.
    Akova, M.
    Arendrup, M. C.
    Arikan-Akdagli, S.
    Bassetti, M.
    Bille, J.
    Cornely, O. A.
    Cuenca-Estrella, M.
    Donnelly, J. P.
    Garbino, J.
    Herbrecht, R.
    Jensen, H. E.
    Kullberg, B. J.
    Lass-Floerl, C.
    Lortholary, O.
    Meersseman, W.
    Petrikkos, G.
    Richardson, M. D.
    Verweij, P. E.
    Viscoli, C.
    Ullmann, A. J.
    [J]. CLINICAL MICROBIOLOGY AND INFECTION, 2012, 18 : 38 - 52