Isolable micelles with a fluid core made of kanamycin A 6′-stearoylamide

被引:6
作者
Gouzy, MF [1 ]
Lauer, M [1 ]
Gonzaga, F [1 ]
Schulz, A [1 ]
Fuhrhop, JH [1 ]
机构
[1] Free Univ Berlin, Inst Chem Organ, D-14195 Berlin, Germany
关键词
D O I
10.1021/la0205250
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Kanamycin, a pseudo-trisaccharide bearing four amino groups, was monoamidated with stearic acid. This amphiphile with a broad headgroup capable of forming +NH3-OH hydrogen bonds in aqueous solution and a narrow hydrophobic moiety produces micelles. They dissolve a hydrophobic porphyrin in water, and they are stable in the dry form. TEM and AFM pictures of these first isolable micelles with a fluid core are discussed.
引用
收藏
页码:10091 / 10094
页数:4
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