Bibliometric Insights in Genetic Factors of Substance-Related Disorders: Intellectual Developments, Turning Points, and Emerging Trends

被引:2
作者
Wang, Kang [1 ]
Duan, Yijie [1 ]
Duan, Weicheng [1 ]
Yu, Yuxin [2 ]
Zheng, Na [3 ]
Hu, Jin [4 ]
He, Jia [5 ]
Chen, Haihong [6 ]
Liang, Man [1 ]
机构
[1] Huazhong Univ Sci & Technol, Dept Forens Med, Tongji Med Coll, Wuhan, Peoples R China
[2] Huazhong Univ Sci & Technol, Dept Endocrinol, Union Hosp, Tongji Med Coll, Wuhan, Peoples R China
[3] Shenzhen Univ, Dept Pathol, Hlth Sci Ctr, Shenzhen, Peoples R China
[4] Huazhong Univ Sci & Technol, Dept Otolaryngol Head & Neck Surg, Tonji Hosp, Tongji Med Coll, Wuhan, Peoples R China
[5] Shihezi Univ, Dept Publ Hlth, Sch Med, Shihezi, Peoples R China
[6] Nanjing Med Univ, Sch Hlth Policy & Management, Nanjing, Peoples R China
来源
FRONTIERS IN PSYCHIATRY | 2021年 / 12卷
基金
中国国家自然科学基金;
关键词
bibliometric; substance-related disorder; genetics; quantitative analysis; research frontiers; GENOME-WIDE ASSOCIATION; ALCOHOL DEPENDENCE; BRADFORD LAW; DRUG-ABUSE; GABRA2; RISK; ADDICTION; VULNERABILITY; EPIDEMIOLOGY; COOCCURRENCE;
D O I
10.3389/fpsyt.2021.620489
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Substance-related disorders are a group of medical conditions that affect a person's brain and behavior and lead to an inability to control the use of legal or illegal drug(s) or medication. Substance-related disorder is a serious public health and society problem worldwide. Genetic factors have been proven to have an important role. Researchers have carried out a lot of work in this field, and a large number of research results have been published in academic journals around the world. However, there are few overviews of research progress, presentation, and development trends in this field. In this study, a total of 636 articles related to genetic factors of substance-related disorders were retrieved from the Web of Science (WoS) database from 1997 to 2018, and the scientific literatures were analyzed by bibliometrics. The study found that the United States (US) has maintained a leading position in the field of research, with many core institutions and plenty of high-quality research results. Alcohol use disorder is still the most concerning issue in this field. Over the past 20 years, new techniques such as genome-wide association study (GWAS) based on high-throughput sequencing technology have replaced family studies, twin studies, and retrospective studies in this field. We believe that it is urgent to study the genetic factors of substance-related disorders, which can greatly deepen the understanding of the pathogenesis of substance-related disorders and may provide potential targets for precise treatment of such diseases.
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页数:12
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