Visualization of Spatial Distribution of γ-Aminobutyric Acid in Eggplant (Solanum melongena) by Matrix-assisted Laser Desorption/Ionization Imaging Mass Spectrometry

被引：51

作者：

Goto-Inoue, Naoko ^{[1
]}

Setou, Mitsutoshi ^{[1
]}

Zaima, Nobuhiro ^{[1
]}

机构：

[1] Hamamatsu Univ Sch Med, Dept Mol Anat, Hamamatsu, Shizuoka 4313192, Japan

来源：

ANALYTICAL SCIENCES | 2010年 / 26卷 / 07期

关键词：

PRINCIPAL COMPONENT ANALYSIS; BRAIN-TISSUE; PLANT METABOLOMICS; MOUSE-BRAIN; GABA; METABOLITES; REVEALS; SYSTEMS; TOFMS; TIME;

D O I：

10.2116/analsci.26.821

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

We applied imaging mass spectrometry (IMS) to determine the spatial distribution of gamma-aminobutyric acid (GABA). We found that GABA had a specific localization in seeds. We also visualized various biomolecules as well as GABA with higher spatial resolution than in the previous report. Our work suggests that IMS might be a powerful tool for exploring functional food factors, investigating the specific distribution of nutrients in unused natural resources, and evaluating the quality of functional foods.

引用

页码：821 / 825

页数：5

共 34 条

[31] GABA, γ-hydroxybutyric acid, and neurological disease
Wong, CGT
Bottiglieri, T
Snead, OC
[J]. ANNALS OF NEUROLOGY, 2003, 54 : S3 - S12
[32] In situ proteomics with imaging mass spectrometry and principal component analysis in the Scrapper-knockout mouse brain
Yao, Ikuko
Sugiura, Yuki
Matsumoto, Mineo
Setou, Mitsutoshi
[J]. PROTEOMICS, 2008, 8 (18) : 3692 - 3701
[33] Imaging of Metabolites by MALDI Mass Spectrometry
Zaima, Nobuhiro
Hayasaka, Takahiro
Goto-Inoue, Naoko
Setou, Mitsutoshi
[J]. JOURNAL OF OLEO SCIENCE, 2009, 58 (08) : 415 - 419
[34] Principal Component Analysis of Direct Matrix-Assisted Laser Desorption/Ionization Mass Spectrometric Data Related to Metabolites of Fatty Liver
Zaima, Nobuhiro
Matsuyama, Yumiko
Setou, Mitsutoshi
[J]. JOURNAL OF OLEO SCIENCE, 2009, 58 (05) : 267 - 273

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