Visualization of Spatial Distribution of γ-Aminobutyric Acid in Eggplant (Solanum melongena) by Matrix-assisted Laser Desorption/Ionization Imaging Mass Spectrometry

被引：51

作者：

Goto-Inoue, Naoko ^{[1
]}

Setou, Mitsutoshi ^{[1
]}

Zaima, Nobuhiro ^{[1
]}

机构：

[1] Hamamatsu Univ Sch Med, Dept Mol Anat, Hamamatsu, Shizuoka 4313192, Japan

来源：

ANALYTICAL SCIENCES | 2010年 / 26卷 / 07期

关键词：

PRINCIPAL COMPONENT ANALYSIS; BRAIN-TISSUE; PLANT METABOLOMICS; MOUSE-BRAIN; GABA; METABOLITES; REVEALS; SYSTEMS; TOFMS; TIME;

D O I：

10.2116/analsci.26.821

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

We applied imaging mass spectrometry (IMS) to determine the spatial distribution of gamma-aminobutyric acid (GABA). We found that GABA had a specific localization in seeds. We also visualized various biomolecules as well as GABA with higher spatial resolution than in the previous report. Our work suggests that IMS might be a powerful tool for exploring functional food factors, investigating the specific distribution of nutrients in unused natural resources, and evaluating the quality of functional foods.

引用

页码：821 / 825

页数：5

共 34 条

[11] Plant reproduction: GABA gradient, guidance and growth
Hong, M
[J]. CURRENT BIOLOGY, 2003, 13 (21) : R834 - R836
[12] Direct profiling of lipid distribution in brain tissue using MALDI-TOFMS
Jackson, SN
Wang, HYJ
Woods, AS
[J]. ANALYTICAL CHEMISTRY, 2005, 77 (14) : 4523 - 4527
[13] Direct molecular analysis of whole-body animal tissue sections by imaging MALDI mass spectrometry
Khatib-Shahidi, Sheerin
Andersson, Malin
Herman, Jennifer L.
Gillespie, Todd A.
Caprioli, Richard M.
[J]. ANALYTICAL CHEMISTRY, 2006, 78 (18) : 6448 - 6456
[14] Atmospheric pressure infrared MALDI imaging mass spectrometry for plant metabolomics
Li, Yue
Shrestha, Bindesh
Vertes, Akos
[J]. ANALYTICAL CHEMISTRY, 2008, 80 (02) : 407 - 420
[15] Atmospheric pressure molecular imaging by infrared MALDI mass spectrometry
Li, Yue
Shrestha, Bindesh
Vertes, Akos
[J]. ANALYTICAL CHEMISTRY, 2007, 79 (02) : 523 - 532
[16] Gas chromatography mass spectrometry-based metabolite profiling in plants
Lisec, Jan
Schauer, Nicolas
Kopka, Joachim
Willmitzer, Lothar
Fernie, Alisdair R.
[J]. NATURE PROTOCOLS, 2006, 1 (01) : 387 - 396
[17] Subcellular imaging mass spectrometry of brain tissue
McDonnell, LA
Piersma, SR
Altelaar, AFM
Mize, TH
Luxembourg, SL
Verhaert, PDEM
van Minnen, J
Heeren, RMA
[J]. JOURNAL OF MASS SPECTROMETRY, 2005, 40 (02): : 160 - 168
[18] Effects of germinated brown rice extracts with enhanced levels of GABA on cancer cell proliferation and apoptosis
Oh, CH
Oh, SH
[J]. JOURNAL OF MEDICINAL FOOD, 2004, 7 (01) : 19 - 23
[19] Oh Suk-Heung, 2003, Journal of Medicinal Food, V6, P115
[20] Metabonomic analysis of mouse urine by liquid-chromatography-time of flight mass spectrometry (LC-TOFMS): detection of strain, diurnal and gender differences
Plumb, R
Granger, J
Stumpf, C
Wilson, ID
Evans, JA
Lenz, EM
[J]. ANALYST, 2003, 128 (07) : 819 - 823

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