Visualization of Spatial Distribution of γ-Aminobutyric Acid in Eggplant (Solanum melongena) by Matrix-assisted Laser Desorption/Ionization Imaging Mass Spectrometry

被引:51
作者
Goto-Inoue, Naoko [1 ]
Setou, Mitsutoshi [1 ]
Zaima, Nobuhiro [1 ]
机构
[1] Hamamatsu Univ Sch Med, Dept Mol Anat, Hamamatsu, Shizuoka 4313192, Japan
关键词
PRINCIPAL COMPONENT ANALYSIS; BRAIN-TISSUE; PLANT METABOLOMICS; MOUSE-BRAIN; GABA; METABOLITES; REVEALS; SYSTEMS; TOFMS; TIME;
D O I
10.2116/analsci.26.821
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
We applied imaging mass spectrometry (IMS) to determine the spatial distribution of gamma-aminobutyric acid (GABA). We found that GABA had a specific localization in seeds. We also visualized various biomolecules as well as GABA with higher spatial resolution than in the previous report. Our work suggests that IMS might be a powerful tool for exploring functional food factors, investigating the specific distribution of nutrients in unused natural resources, and evaluating the quality of functional foods.
引用
收藏
页码:821 / 825
页数:5
相关论文
共 34 条
  • [1] GABA in plants:: just a metabolite?
    Bouché, N
    Fromm, H
    [J]. TRENDS IN PLANT SCIENCE, 2004, 9 (03) : 110 - 115
  • [2] Colloidal graphite-assisted laser desorption/ionization mass spectrometry and MSn of small molecules.: 1.: Imaging of cerebrosides directly from rat brain tissue
    Cha, Sangwon
    Yeung, Edward S.
    [J]. ANALYTICAL CHEMISTRY, 2007, 79 (06) : 2373 - 2385
  • [3] MALDI imaging mass spectrometry: molecular snapshots of biochemical systems
    Cornett, Dale S.
    Reyzer, Michelle L.
    Chaurand, Pierre
    Caprioli, Richard M.
    [J]. NATURE METHODS, 2007, 4 (10) : 828 - 833
  • [4] The role of mass spectrometry in plant systems biology
    Glinski, M
    Weckwerth, W
    [J]. MASS SPECTROMETRY REVIEWS, 2006, 25 (02) : 173 - 214
  • [5] The specific localization of seminolipid molecular species on mouse testis during testicular maturation revealed by imaging mass spectrometry
    Goto-Inoue, Naoko
    Hayasaka, Takahiro
    Zaima, Nobuhiro
    Setou, Mitsutoshi
    [J]. GLYCOBIOLOGY, 2009, 19 (09) : 950 - 957
  • [6] Han D, 2007, J MICROBIOL BIOTECHN, V17, P1661
  • [7] Visualization of Volatile Substances in Different Organelles with an Atmospheric-Pressure Mass Microscope
    Harada, Takahiro
    Yuba-Kubo, Akiko
    Sugiura, Yuki
    Zaima, Nobuhiro
    Hayasaka, Takahiro
    Goto-Inoue, Naoko
    Wakui, Masatoshi
    Suematsu, Makoto
    Takeshita, Kengo
    Ogawa, Kiyoshi
    Yoshida, Yoshikazu
    Setou, Mitsutoshi
    [J]. ANALYTICAL CHEMISTRY, 2009, 81 (21) : 9153 - 9157
  • [8] Matrix-assisted laser desorption/ionization quadrupole ion trap time-of-flight (MALDI-QIT-TOF)-based imaging mass spectrometry reveals a layered distribution of phospholipid molecular species in the mouse retina
    Hayasaka, Takahiro
    Goto-Inoue, Naoko
    Sugiura, Yuki
    Zaima, Nobuhiro
    Nakanish, Hiroki
    Ohishi, Kentaro
    Nakanish, Setsuko
    Naito, Takayuki
    Taguchi, Ryo
    Setou, Mitsutoshi
    [J]. RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2008, 22 (21) : 3415 - 3426
  • [9] Organ-Specific Distributions of Lysophosphatidylcholine and Triacylglycerol in Mouse Embryo
    Hayasaka, Takahiro
    Goto-Inoue, Naoko
    Zaima, Nobuhiro
    Kimura, Yoshishige
    Setou, Mitsutoshi
    [J]. LIPIDS, 2009, 44 (09) : 837 - 848
  • [10] Proteome imaging: A closer look at life's organization
    Heeren, RMA
    [J]. PROTEOMICS, 2005, 5 (17) : 4316 - 4326