The double-edged sword of evolution

被引：4

作者：

Kruzel-Davila, Etty ^{[1
]}

Skorecki, Karl ^{[2
,3
]}

机构：

[1] Rambam Hlth Care Campus, Dept Nephrol, Haifa, Israel

[2] Rambam Hlth Care Campus, Dept Med & Res Dev, Haifa, Israel

[3] Technion Israel Inst Technol, Rappaport Fac Med, Haifa, Israel

来源：

ELIFE | 2017年 / 6卷

基金：

英国惠康基金;

关键词：

HUMAN SERUM; APOL1;

D O I：

10.7554/eLife.29056

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Two gene variants provide different levels of protection against sleeping sickness, but this comes with an increased risk of developing chronic kidney disease. © 2017, eLife Sciences Publications Ltd. All rights reserved.

引用

页数：3

共 9 条

[1] Human host determinants influencing the outcome of Trypanosoma brucei gambiense infections [J].

Bucheton, B. ;

MacLeod, A. ;

Jamonneau, V. .

PARASITE IMMUNOLOGY, 2011, 33 (08) :438-447

[2]

Cooper A, 2017, ELIFE, V6, DOI [10.7554/eLife.25461, 10.7554/elife.25461]

[3] Association of Trypanolytic ApoL1 Variants with Kidney Disease in African Americans [J].

Genovese, Giulio ;

Friedman, David J. ;

Ross, Michael D. ;

Lecordier, Laurence ;

Uzureau, Pierrick ;

Freedman, Barry I. ;

Bowden, Donald W. ;

Langefeld, Carl D. ;

Oleksyk, Taras K. ;

Knob, Andrea L. Uscinski ;

Bernhardy, Andrea J. ;

Hicks, Pamela J. ;

Nelson, George W. ;

Vanhollebeke, Benoit ;

Winkler, Cheryl A. ;

Kopp, Jeffrey B. ;

Pays, Etienne ;

Pollak, Martin R. .

SCIENCE, 2010, 329 (5993) :841-845

[4]

Ilboudo H, 2014, PLOS PATHOG, V10, DOI [10.1371/journal.ppat. 1004469, DOI 10.1371/JOURNAL.PPAT.1004469]

[5] The molecular arms race between African trypanosomes and humans [J].

Pays, Etienne ;

Vanhollebeke, Benoit ;

Uzureau, Pierrick ;

Lecordier, Laurence ;

Perez-Morga, David .

NATURE REVIEWS MICROBIOLOGY, 2014, 12 (08) :575-584

[6] Evolution of the primate trypanolytic factor APOL1 [J].

Thomson, Russell ;

Genovese, Giulio ;

Canon, Chelsea ;

Kovacsics, Daniella ;

Higgins, Matthew K. ;

Carrington, Mark ;

Winkler, Cheryl A. ;

Kopp, Jeffrey ;

Rotimi, Charles ;

Adeyemo, Adebowale ;

Doumatey, Ayo ;

Ayodo, George ;

Alper, Seth L. ;

Pollak, Martin R. ;

Friedman, David J. ;

Raper, Jayne .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, 111 (20) :E2130-E2139

[7] Missense mutations in the APOL1 gene are highly associated with end stage kidney disease risk previously attributed to the MYH9 gene [J].

Tzur, Shay ;

Rosset, Saharon ;

Shemer, Revital ;

Yudkovsky, Guennady ;

Selig, Sara ;

Tarekegn, Ayele ;

Bekele, Endashaw ;

Bradman, Neil ;

Wasser, Walter G. ;

Behar, Doron M. ;

Skorecki, Karl .

HUMAN GENETICS, 2010, 128 (03) :345-350

[8] Mechanism of Trypanosoma brucei gambiense resistance to human serum [J].

Uzureau, Pierrick ;

Uzureau, Sophie ;

Lecordier, Laurence ;

Fontaine, Frederic ;

Tebabi, Patricia ;

Homble, Fabrice ;

Grelard, Axelle ;

Zhendre, Vanessa ;

Nolan, Derek P. ;

Lins, Laurence ;

Crowet, Jean-Marc ;

Pays, Annette ;

Felu, Cecile ;

Poelvoorde, Philippe ;

Vanhollebeke, Benoit ;

Moestrup, Soren K. ;

Lyngso, Jeppe ;

Pedersen, Jan Skov ;

Mottram, Jeremy C. ;

Dufourc, Erick J. ;

Perez-Morga, David ;

Pays, Etienne .

NATURE, 2013, 501 (7467) :430-+

[9] Apolipoprotein L-I is the trypanosome lytic factor of human serum [J].

Vanhamme, L ;

Paturiaux-Hanocq, F ;

Poelvoorde, P ;

Nolan, DP ;

Lins, L ;

Van den Abbeele, J ;

Pays, A ;

Tebabi, P ;

Van Xong, H ;

Jacquet, A ;

Moguilevsky, N ;

Dieu, M ;

Kane, JP ;

De Baetselier, P ;

Brasseur, R ;

Pays, E .

NATURE, 2003, 422 (6927) :83-87

← 1 →