Zn-proline catalyzed direct aldol reaction in aqueous media

被引：199
作者：
Darbre, T [1 ]
Machuqueiro, M [1 ]
机构：
[1] Univ Bern, Dept Chem & Biochem, CH-3012 Bern, Switzerland
来源：
CHEMICAL COMMUNICATIONS | 2003年 / 09期
关键词：
D O I：
10.1039/b301117h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Zn complexes of proline, lysine and arginine are efficient catalysts for the aldol addition of p-nitrobenzaldehyde and acetone in aqueous medium, giving quantitative yields and enantiomeric excesses up to 56% with 5 mol% of the catalysts at room temperature.
引用
收藏
页码：1090 / 1091
页数：2
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