Metal-assisted multicomponent reactions involving carbon monoxide - Towards heterocycle synthesis

被引:66
作者
Mihovilovic, Marko D. [1 ]
Stanetty, Peter [1 ]
机构
[1] Vienna Univ Technol, Inst Appl Synth Chem, A-1060 Vienna, Austria
关键词
carbon monoxide; heterocycles; multicomponent reactions; synthetic methods; transition metals;
D O I
10.1002/anie.200604743
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
An assembly line for heterocycles: Multicomponent reactions have become a highly valuable tool for the generation of compound libraries particularly of heterocyclic drug candidates. In particular, metal-assisted transformations have enabled the further extension of established methods and development of new strategies. This Highlight presents some innovative examples in which carbon monoxide is used to generate diverse heterocycles. (Figure Presented). © 2007 Wiley-VCH Verlag GmbH &. Co. KGaA.
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页码:3612 / 3615
页数:4
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