Synthesis, Characterization and Biological Evaluation of Some Dihydropyrimidinones

被引：0
|
作者：
Vijay, K. [1 ]
Ganapaty, S. [1 ]
Rao, A. Srinivas [1 ]
机构：
[1] Andhra Univ, Univ Coll Pharmaceut Sci, Visakhapatnam 530003, Andhra Pradesh, India
来源：
ASIAN JOURNAL OF CHEMISTRY | 2010年 / 22卷 / 04期
关键词：
Biginelli compounds; Citric acid; Anticancer activity; Antiinflammatory activity; ESTERS; ACID;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An efficient and facile one pot synthesis of 3,4-dihydropyrimidinones (Biginelli compounds) from divergent aldehydes, beta-keto esters and urea or thiourea under solvent free conditions was performed using citric acid as catalyst, resulted in promising yields. These compounds were subjected for anticancer and anti inflammatory activities which showed significant activities.
引用
收藏
页码：2518 / 2528
页数：11
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