REGRESSION OF PRIMARY CENTRAL NERVOUS SYSTEM GERMINOMA AFTER DEXAMETHASONE ADMINISTRATION: A Case Report

被引：7

作者：

Si, Stephanie J. ^{[1
]}

Khatua, Soumen ^{[1
]}

Dhall, Girish ^{[1
]}

Nelson, Marvin D. ^{[2
]}

Gonzalez-Gomez, Ignacio ^{[3
]}

Finlay, Jonathan L. ^{[1
]}

机构：

[1] Childrens Hosp Los Angeles, Neural Tumors Program, Childrens Ctr Canc & Blood Dis, Los Angeles, CA 90027 USA

[2] Childrens Hosp Los Angeles, Dept Radiol, Los Angeles, CA 90027 USA

[3] Childrens Hosp Los Angeles, Dept Pathol & Lab Med, Los Angeles, CA 90027 USA

来源：

PEDIATRIC HEMATOLOGY AND ONCOLOGY | 2010年 / 27卷 / 03期

关键词：

CNS germinoma dexamethasone; tumor shrinkage; GERM-CELL TUMORS; RADIATION-THERAPY;

D O I：

10.3109/08880010903544866

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Childhood central nervous system (CNS) germinoma are highly curable brain tumors characterized pathologically by varying degrees of lymphocytic infiltration. The authors present a case of a CNS germinoma with significant regression in size following surgery and administration of dexamethasone, prior to initiation of chemotherapy or irradiation. The authors speculate the possible mechanism involved in its occurrence. Perioperative corticosteroid administration in patients with CNS germinoma may obfuscate the increase in response demonstrated with various chemotherapy regimens or with irradiation in CNS germinomas.

引用

页码：237 / 243

页数：7

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