Polymer based lab-on-a-chip lasers

被引:2
|
作者
Kristensen, A [1 ]
Balslev, S [1 ]
Bilenberg, B [1 ]
Gersborg-Hansen, M [1 ]
Nilsson, D [1 ]
机构
[1] Tech Univ Denmark, MIC, Dept Micro & Nanotechnol, DK-2800 Lyngby, Denmark
来源
LAB - ON - A - CHIP: PLATFORMS, DEVICES, AND APPLICATIONS | 2004年 / 5591卷
关键词
laser; dye; tunable; polymer; lab-on-a-chip;
D O I
10.1117/12.577620
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The integration of optical transducers is generally considered a key issue in the further development of lab-on-a-chip Microsystems. We present a technology for miniaturized, polymer based lasers, suitable for integration with planar waveguides and microfluidic networks. The lasers rely on the commercial laser dye Rhodamine 6G as active medium, and the laser resonator is defined in a thin film of polymer on a low refractive index substrate. Two types of devices are demonstrated: solid and microfluidic polymer based dye lasers. In the microfluidic dye lasers, the laser dye is dissolved in a suitable solvent and flushed though a microfluidic channel, which has the laser resonator embedded. For solid state dye lasers, the laser dye is dissolved in the polymer forming the laser resonator. The miniaturized dye lasers are optically pumped by a frequency doubled, pulsed Nd:YAG laser (at 532 nm), and emit at wavelengths between 560 nm and 590 nm. The lasers emit in the plane of the chip, and the emitted light is coupled into planar polymer waveguides on the chip. The feasibility of three types of polymers is demonstrated: SU-8, P-MMA and a cyclo-olefin co-polymer (COC) - Topas. SU-8 is a negative tone photoresist, allowing patterning with conventional UV lithography. PMMA and Topas are thermoplasts, which are patterned by nanoimprint lithography (NIL). The lasing wavelength of the microfluidic dye lasers can be coarse tuned over 30 nm by varying the concentration of laser dye, and fine tuned by varying the refractive index of the solvent. This is utilized to realize a tunable laser, by on-chip mixing of dye, and two solvents of different index of refraction. The lasers were also integrated with waveguides and microfluidic networks.
引用
收藏
页码:64 / 71
页数:8
相关论文
共 50 条
  • [21] Microplasmas for analytical applications of lab-on-a-chip
    Luo, Daibing
    Duan, Yixiang
    TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 2012, 39 : 254 - 266
  • [22] Water analysis in a lab-on-a-chip system
    Freimuth, Herbert
    von Germar, Frithjof
    Frese, Ines
    Nahrstedt, Elzbieta
    Kuepper, Michael
    Schenk, Rainer
    Baser, Bjoern
    Ott, Johannes
    Drese, Klaus
    Detemple, Peter
    Doll, Theodor
    MICROFLUIDICS, BIOMEMS, AND MEDICAL MICROSYSTEMS IV, 2006, 6112
  • [23] BIOCOMPATIBLE NANOCOMPOSITE FOR LAB-ON-A-CHIP APPLICATION
    Islam, Nazmul
    Askari, Davood
    Trad, Tarek
    PROCEEDINGS OF THE ASME INTERNATIONAL MECHANICAL ENGINEERING CONGRESS AND EXPOSITION, 2011, VOL 8, 2012, : 79 - 82
  • [24] Lab-on-a-Chip for Cardiovascular Physiology and Pathology
    Beverung, Sean
    Wu, Jingwen
    Steward, Robert, Jr.
    MICROMACHINES, 2020, 11 (10)
  • [25] Integrated Optical Microfluidic Lab-on-a-chip
    Chandrasekaran, Arvind
    Packirisamy, Muthukumaran
    PHOTONICS NORTH 2008, 2008, 7099
  • [26] A lab-on-a-chip for cell detection and manipulation
    Medoro, G
    Manaresi, N
    Leonardi, A
    Altomare, L
    Tartagni, M
    Guerrieri, R
    IEEE SENSORS JOURNAL, 2003, 3 (03) : 317 - 325
  • [27] Quantitative analysis of respiratory viruses based on lab-on-a-chip platform
    Zhang, Ning
    Li, Chao
    Zhan, Xiaobo
    Cheng, Zhi
    Li, Chao
    Du, Yaohua
    Tian, Feng
    ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2023, 415 (26) : 6561 - 6571
  • [28] Lab-on-a-Chip With β-Poly(Vinylidene Fluoride) Based Acoustic Microagitation
    Cardoso, V. F.
    Catarino, S. O.
    Nunes, J. Serrado
    Rebouta, L.
    Rocha, J. G.
    Lanceros-Mendez, S.
    Minas, G.
    IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 2010, 57 (05) : 1184 - 1190
  • [29] Quantitative analysis of respiratory viruses based on lab-on-a-chip platform
    Ning Zhang
    Chao Yue
    Xiaobo Zhan
    Zhi Cheng
    Chao Li
    Yaohua Du
    Feng Tian
    Analytical and Bioanalytical Chemistry, 2023, 415 : 6561 - 6571
  • [30] Smartphone-Based lab-on-a-chip sensor for flu detection
    Yoon, J.-Y. (jyyoon@email.arizona.edu), 1600, American Society of Agricultural and Biological Engineers (21):