Diffuse Alveolar Hemorrhage Associated with Dilated Cardiomyopathy and Sleep Apnea Syndrome

被引：2

作者：

Suematsu, Ryohei ^{[1
]}

Miyata, Jun ^{[1
]}

Sano, Tomoya ^{[1
]}

Watanabe, Chie ^{[1
]}

Maki, Yohei ^{[1
]}

Kimizuka, Yoshifumi ^{[1
]}

Hayashi, Nobuyoshi ^{[1
]}

Fujikura, Yuji ^{[1
]}

Sugiura, Hiroaki ^{[2
]}

Shinmoto, Hiroshi ^{[2
]}

Taruoka, Akira ^{[3
]}

Nagatomo, Yuji ^{[3
]}

Adachi, Takeshi ^{[3
]}

Kawana, Akihiko ^{[1
]}

机构：

[1] Natl Def Med Coll, Dept Internal Med, Div Infect Dis & Resp Med, Tokorozawa, Saitama, Japan

[2] Natl Def Med Coll, Dept Radiol, Tokorozawa, Saitama, Japan

[3] Natl Def Med Coll, Dept Internal Med, Div Cardiovasc Med, Tokorozawa, Saitama, Japan

来源：

INTERNAL MEDICINE | 2021年 / 60卷 / 12期

关键词：

diffuse alveolar hemorrhage; dilated cardiomyopathy; anemia; sleep apnea syndrome; negative pressure pulmonary hemorrhage; IDIOPATHIC PULMONARY HEMOSIDEROSIS;

D O I：

10.2169/internalmedicine.5219-20

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We herein report a case of diffuse alveolar hemorrhage (DAH) associated with dilated cardiomyopathy (DCM) and sleep apnea syndrome (SAS) in a 47-year-old man. The patient exhibited recurring dyspnea and bloody sputum. Chest radiography showed bilateral diffuse infiltrative opacities without pleural effusion. A bronchoscopic analysis of bronchoalveolar lavage fluid revealed hemosiderin-laden macrophages. Based on these findings, he was diagnosed with DAH. Laboratory and pathological findings ruled out the possibility of collagen diseases and vasculitis. Overnight polysomnography revealed concomitant severe obstructive SAS. Treatment with continuous positive-pressure ventilation and pharmacological therapy for DCM prevented recurrence of DAH.

引用

页码：1911 / 1914

页数：4

共 19 条

[1] Sleep-disordered breathing in patients with idiopathic cardiomyopathy [J].

Banno, K ;

Shiomi, T ;

Sasanabe, R ;

Otake, K ;

Hasegawa, R ;

Maekawa, M ;

Ito, T .

CIRCULATION JOURNAL, 2004, 68 (04) :338-342

[2] Idiopathic pulmonary hemosiderosis in adults: review of cases reported in the latest 15 years [J].

Chen, Xi-Yuan ;

Sun, Jin-Ming ;

Huang, Xiao-Jun .

CLINICAL RESPIRATORY JOURNAL, 2017, 11 (06) :677-681

[3]

Colby T V, 2001, Ann Diagn Pathol, V5, P309, DOI 10.1053/adpa.2001.27923

[4] Clinical Features of Patients with Diffuse Alveolar Hemorrhage due to Negative-Pressure Pulmonary Edema [J].

Contou, Damien ;

Voiriot, Guillaume ;

Djibre, Michel ;

Labbe, Vincent ;

Fartoukh, Muriel ;

Parrot, Antoine .

LUNG, 2017, 195 (04) :477-487

[5] Diffuse alveolar haemorrhage: factors associated with in-hospital and long-term mortality [J].

de Prost, N. ;

Parrot, A. ;

Picard, C. ;

Ancel, P-Y. ;

Mayaud, C. ;

Fartoukh, M. ;

Cadranel, J. .

EUROPEAN RESPIRATORY JOURNAL, 2010, 35 (06) :1303-1311

[6] Idiopathic pulmonary haemosiderosis revisited [J].

Ioachimescu, OC ;

Sieber, S ;

Kotch, A .

EUROPEAN RESPIRATORY JOURNAL, 2004, 24 (01) :162-170

[7]

Isikay S, 2012, BMJ CASE REP, Vbcr

[8] Diffuse alveolar haemorrhage with predominant upper lung lobe involvement associated with congestive heart failure: a case series [J].

Jonckheer, Joop ;

Slabbynck, Hans ;

Spapen, Herbert .

JOURNAL OF THORACIC DISEASE, 2017, 9 (10) :3956-3960

[9] A young man with hemoptysis: Rare association of idiopathic pulmonary hemosiderosis, celiac disease and dilated cardiomyopathy [J].

Khilnani, Gopi C. ;

Jain, Neetu ;

Tiwari, Pavan ;

Hadda, Vijay ;

Singh, Lavleen .

LUNG INDIA, 2015, 32 (01) :70-72

[10] Diffuse Alveolar Hemorrhage [J].

Lara, Abigail R. ;

Schwarz, Marvin I. .

CHEST, 2010, 137 (05) :1164-1171

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