Synthesis of blood compatible PDMS-based organic-inorganic hybrid coatings

被引：16

作者：

Yabuta, T ^{[1
]}

Tsuru, K ^{[1
]}

Hayakawa, S ^{[1
]}

Osaka, A ^{[1
]}

机构：

[1] Okayama Univ, Fac Engn, Biomat Lab, Okayama 7008530, Japan

来源：

JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY | 2004年 / 31卷 / 1-3期

关键词：

organic-inorganic hybrid coating; blood compatibility; blood clotting property; platelet adhesion;

D O I：

10.1023/B:JSST.0000048002.65187.3a

中图分类号：

TQ174 [陶瓷工业]; TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

PDMS- TiO2 hybrid coating sols were prepared from silanol- terminated polydimethylsiloxane and titanium tetraisopropoxide through sol- gel process. The coating sols were developed on stainless steel substrate with dip- coating technique. The surface structure of the hybrid coating was characterized by Fourier transform infrared ( FT- IR) analysis, contact angle, and surface free energy on the hybrid coating. Blood compatibility was also evaluated in terms of blood clotting time and platelet adhesion. The hybrid coatings have high contact angles and low surface free energies compared to coating- free metal surface. The blood clotting properties were not affected by the hybrid coatings but the platelet adhesion was depressed to less than 1/ 20 as much as that for the coating- free substrate.

引用

页码：273 / 276

页数：4

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