HER2-positive advanced breast cancer

被引：5
|
作者：
Robert, Nicholas J. [1 ]
Favret, Anne M. [1 ]
机构：
[1] US Oncol Res Network, Fairfax No Virginia Hematol Oncol, Fairfax, VA 22031 USA
来源：
HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA | 2007年 / 21卷 / 02期
关键词：
D O I：
10.1016/j.hoc.2007.03.010
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
It is important when treating a patient who has advanced breast cancer to establish the biologic characteristics of the tumor. In addition to knowing the hormone receptor status (estrogen and progesterone), human epidermal receptor 2 (HER2) should be evaluated. The measurement of this parameter is essential to optimizing the systemic management. This article reviews the biology of HER2, testing for HER2, clinical studies evaluating HER2-based therapies, side effects (specifically cardiotoxicity), and strategies for HER2-based therapies.
引用
收藏
页码：293 / +
页数：12
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