Cryptosporidiosis outbreak in visitors of a UK industry-compliant petting farm caused by a rare Cryptosporidium parvum subtype: a case-control study

被引：17

作者：

Utsi, L. ^{[1
]}

Smith, S. J. ^{[2
]}

Chalmers, R. M. ^{[3
]}

Padfield, S. ^{[1
]}

机构：

[1] Publ Hlth England, Field Epidemiol Serv, Blenheim House,West One,Duncombe St, Leeds, W Yorkshire, England

[2] Yorkshire & Humber Publ Hlth England Ctr, Hlth Protect Team, Leeds, W Yorkshire, England

[3] Publ Hlth Wales Microbiol, Cryptosporidium Reference Unit, Swansea, W Glam, Wales

来源：

EPIDEMIOLOGY AND INFECTION | 2016年 / 144卷 / 05期

关键词：

Cryptosporidium; hand hygiene; outbreaks; public health; zoonoses; ZOONOTIC CRYPTOSPORIDIOSIS; DAIRY-CATTLE; INFECTION; ENGLAND; HUMANS; WALES; EPIDEMIOLOGY; TRANSMISSION; PREVALENCE; CHILDREN;

D O I：

10.1017/S0950268815002319

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

A case-control study was conducted to investigate an outbreak of 46 cases of cryptosporidiosis in visitors to a petting farm in England. Details of exposures on the farm were collected for 38 cases and 39 controls, recruited through snowball sampling. Multivariable logistic regression identified that cases were 5.5 times more likely than controls to have eaten without washing their hands [95% confidence interval (CI) 1.51-19.9, P = 0.01] and 10 times less likely to report being informed of risk of infection on arrival (odds ratio 0.10, 95% CI 0.01-0.71, P = 0.02). An uncommon Cryptosporidium parvum gp60 subtype (IIaA19G1R1) was identified in a lamb faecal sample and all subtyped cases (n = 22). We conclude that lack of verbal advice and non-compliance with hand washing are significantly associated with a risk of cryptosporidiosis on open farms. These findings highlight the public health importance of effectively communicating risk to petting farm visitors in order to prevent future outbreaks of zoonotic infections.

引用

页码：1000 / 1009

页数：10