Near-infrared spectroscopy for medical applications: Current status and future perspectives

被引：166
作者：
Sakudo, Akikazu [1 ]
机构：
[1] Univ Ryukyus, Fac Med, Sch Hlth Sci, Lab Biometabol Chem, 207 Uehara, Nishihara, Okinawa 9030215, Japan
来源：
CLINICA CHIMICA ACTA | 2016年 / 455卷
基金：
日本学术振兴会;
关键词：
Near-infrared spectroscopy; Vibration; Principal component analysis; Chemometrics; Partial least squares regression; Non-invasive analysis; CHRONIC-FATIGUE; BLOOD-GLUCOSE; METABOLIC MYOPATHIES; REFLECTANCE SPECTROSCOPY; NONINVASIVE MEASUREMENT; CEREBRAL OXYGENATION; OPTICAL PATHLENGTH; MUSCLE METABOLISM; BRAIN ACTIVATION; WATER-CONTENT;
D O I：
10.1016/j.cca.2016.02.009
中图分类号：
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
The near-infrared radiation (NIR) window, also known as the "optical window" or "therapeutic window", is the range of wavelengths that has the maximum depth of penetration in tissue. Indeed, because NIR is minimally absorbed by water and hemoglobin, spectra readings can be easily collected from the body surface. Recent reports have shown the potential of NIR spectroscopy in various medical applications, including functional analysis of the brain and other tissues, as well as an analytical tool for diagnosing diseases. The broad applicability of NIR spectroscopy facilitates the diagnosis and therapy of diseases as well as elucidating their pathophysiology. This review introduces recent advances and describes new studies in NIR to demonstrate potential clinical applications of NIR spectroscopy. (C) 2016 Elsevier B.V. All rights reserved.
引用
收藏
页码：181 / 188
页数：8
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