Determination of susceptibilities of 26 Leptospira sp serovars to 24 antimicrobial agents by a broth microdilution technique

被引：41

作者：

Murray, CK ^{[1
]}

Hospenthal, DR ^{[1
]}

机构：

[1] Brooke Army Med Ctr, Dept Med, Infect Dis Serv, Ft Sam Houston, TX 78234 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2004年 / 48卷 / 10期

关键词：

D O I：

10.1128/AAC.48.10.4002-4005.2004

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The MICs of 24 antimicrobials for 26 Leptospira spp. serovars were determined using a broth microdilution technique. The MICs at which 90% of isolates tested were inhibited (MIC(90)s) of cefepime, imipenem-cilastatin, erythromycin, clarithromycin, and telithromycin were all less than or equal to0.01 mug/ml. The MIC(90)s of amoxicillin, aztreonam, cefdinir, chloramphenicol, and penicillin G were greater than or equal to3.13 mug/ml. Many antimicrobials have excellent in vitro activity against Leptospira.

引用

页码：4002 / 4005

页数：4

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