Ring-closing metathesis in flavonoid synthesis, part 1: flavenes

被引：4

作者：

Pieterse, Tanya ^{[1
]}

Marais, Charlene ^{[1
]}

Bezuidenhoudt, Barend C. B. ^{[1
]}

机构：

[1] Univ Free State, Dept Chem, POB 339, ZA-9300 Bloemfontein, South Africa

来源：

ARKIVOC | 2022年

关键词：

Flavonoid; phenylchroman; flavene; methylenation; metathesis; Grubbs catalyst;

D O I：

10.24820/ark.5550190.p011.733

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Tebbe methylenation and ring-closing metathesis with Grubbs second generation catalyst were investigated as key steps in the synthesis of flav-2-enes with natural substitution patterns. The effect of aromatic substituents on the electron densities of the allyl and vinyl moieties and the effect thereof on methylenation and ring closing metathesis, is discussed.

引用

页码：98 / 113

页数：16