Manual and automated intima-media thickness and diameter measurements of the common carotid artery in patients with renal failure disease

被引：12

作者：

Loizou, Christos P. ^{[1
,2
]}

Kasparis, Takis ^{[2
]}

Lazarou, Theodoros ^{[3
]}

Pattichis, Constandinos S. ^{[4
]}

Pantziaris, Marios ^{[5
]}

机构：

[1] Intercollege, Dept Comp Sci, CY-3507 Limassol, Cyprus

[2] Cyprus Univ Technol, Dept Elect Comp Engn & Informat, Limassol, Cyprus

[3] Limassol Gen Hosp, Nephrol Clin, Limassol, Cyprus

[4] Univ Cyprus, Dept Comp Sci, Nicosia, Cyprus

[5] Cyprus Inst Neurol & Genet, Nicosia, Cyprus

来源：

COMPUTERS IN BIOLOGY AND MEDICINE | 2014年 / 53卷

关键词：

Intima-media thickness; Carotid diameter; Renal failure disease; Ultrasound imaging; Common carotid artery; Segmentation; CHRONIC KIDNEY-DISEASE; RISK-FACTORS; CARDIOVASCULAR-DISEASE; SEGMENTATION; SYSTEM; ATHEROSCLEROSIS; PLAQUES; IMAGES;

D O I：

10.1016/j.compbiomed.2014.08.003

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The objective of this study was to investigate differences in intima-media thickness (IMT) and diameter (D) measurements of the common carotid artery (CCA) in ultrasound imaging in normal subjects and renal failure disease (RFD) patients. Manual measurements by two experts and automated segmentation measurements (based on snakes and active contour models (ACM)) were carried out on 73 normal subjects, and 80 RFD patients. Statistical analysis was carried out using the Wilcoxon rank-sum test at p < 0.05. Results demonstrated that the mean IMT and D measurements were significantly higher for the RFD group versus the normal group. Moreover, there was no significant difference between the manual and automated measurements. The ACM segmentation was slightly more accurate than segmentation based on snakes. Further work is needed to validate these findings on a larger group of subjects. (C) 2014 Elsevier Ltd. All rights reserved.

引用

页码：220 / 229

页数：10

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