Experimental measurement and correlation of the solubility of aloe-emodin in seven pure solvents

被引：12

作者：

Cheng, Yan ^{[1
]}

Wang, Xiao ^{[1
]}

Liu, Wei ^{[1
]}

Wang, Daijie ^{[1
]}

Chen, Lizong ^{[1
]}

机构：

[1] Shandong Anal & Test Ctr, Key Lab TCM Qual Control Technol, Jinan 250014, Peoples R China

来源：

JOURNAL OF CHEMICAL THERMODYNAMICS | 2016年 / 98卷

关键词：

Aloe-emodin; Solubility; Modified Apelblat model; lambda h model; WATER; ANTICANCER; ETHANOL; THERMODYNAMICS; ANTHRAQUINONES; ACETATE;

D O I：

10.1016/j.jct.2016.02.020

中图分类号：

O414.1 [热力学];

学科分类号：

摘要：

The solubility of aloe-emodin in seven pure solvents namely water, methanol, ethanol, 1-propanol, 1-butanol, 2-butanol, and 1-pentanol was measured by a static analytic method. The measurements were carried out over the temperature range from (278.15 to 318.15) K at 5 K intervals under atmospheric pressure using a UV/vis spectrophotometer analysis. The effects of experimental temperature and solvent type on the solubility are discussed. The relative solubility of aloe-emodin in seven solvents was determined in elevated order to be chi(water) (<) chi(methanol) < chi(ethanol) < chi(2-butanol) < chi(1-propanol) < chi(1-butanol) < chi(1-pentanol). The experimental result shows that 1-pentanol could be a suitable solvent for industrial preparation of aloe-emodin. The experimental solubility values were correlated with the modified Apelblat and lambda h models. It was found that the two empirical thermodynamic models can satisfactorily correlate the solubility of aloe-emodin in the seven solvents over the range of temperature studied. (C) 2016 Elsevier Ltd. All rights reserved.

引用

页码：51 / 55

页数：5

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