Evaluation of the hepatoprotective and antioxidant activity of Boehmeria nivea var. nivea and B-nivea var. tenacissima

被引：60

作者：

Lin, CC ^{[1
]}

Yen, MH

Lo, TS

Lin, JM

机构：

[1] Kaohsiung Med Coll, Grad Inst Nat Prod, Kaohsiung, Taiwan

[2] Ziel Enterprise, Kaohsiung, Taiwan

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 1998年 / 60卷 / 01期

关键词：

Boehmeria nivea var. nivea; B-nivea var. tenacissima; hepatoprotective; antioxidative; electron spin resonance (ESR);

D O I：

10.1016/S0378-8741(97)00122-0

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

In this study, the relationship between liver protective effects and antioxidant activity of Boehmeria nivea var. nivea (= B. nivea) and B. nivea var. tenacissima (= B. frutescens) was investigated. The water extracts of both plants exhibited a hepatoprotective activity against CCl4-induced liver injury. B. nivea var. nivea and B. nivea var. tenacissima, also showed anti-oxidant effects in FeCl2-ascorbate induced lipid peroxidation in rat liver homogenate. Moreover, the active oxygen species scavenging potencies were evaluated by an electron spin resonance (ESR) spin-trapping technique. B. nivea var. tenacissima displayed better superoxide radical scavenging activity than B. nivea. Based on these findings, we suggest that in the liver protective and antioxidative effects of B. nivea var. nivea and B. nivea var. tenacissima, possibly involve mechanisms related to free radical scavenging effects. (C) 1998 Elsevier Science Ireland Ltd.

引用

页码：9 / 17

页数：9

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