The road less traveled: how to grow a pancreas transplant program

被引:6
作者
Abrams, Peter [1 ]
Cooper, Matthew [1 ]
Odorico, Jon S. [2 ]
机构
[1] Georgetown Univ, Sch Med, MedStar Georgetown Transplant Inst, Washington, DC USA
[2] Univ Wisconsin, Dept Surg, Div Transplantat, Sch Med & Publ Hlth, Madison, WI USA
关键词
expansion of candidate listing and donor selection criteria; pancreas transplantation; programmatic change; transplant outreach; transplant volume growth; QUALITY-OF-LIFE; KIDNEY-TRANSPLANTATION; DIABETIC-PATIENTS; GRAFT FUNCTION; OUTCOMES; FAILURE; IMPACT; VOLUME; RISK;
D O I
10.1097/MOT.0000000000000556
中图分类号
R3 [基础医学]; R4 [临床医学];
学科分类号
1001 ; 1002 ; 100602 ;
摘要
Purpose of review The volume of pancreas transplants performed annually in the United States (US) has steadily declined for more than a decade. In the face of this negative trend, efforts at several centers are underway to expand their pancreas transplant volumes through alterations in the structure and function of their pancreas transplant programs. We highlight these programmatic changes and emphasize the culture and characteristics of these high volume centers to serve as models for other centers to emulate. As the results of modern-day pancreas transplantation are excellent and continue to improve, pancreas transplant remains an outstanding option for selected patients suffering from diabetes mellitus and end stage renal disease (ESRD) or symptomatic hypoglycemic events (SHEs). Through strong leadership commitment and programmatic restructuring, the transformation of low-volume pancreas transplant centers into high-volume programs is achievable without the need for cost-prohibitive investment. Recent findings Multiple examples may be cited of transplant centers reinvigorating their pancreas transplant programs, increasing their pancreas transplant evaluations and transplant rates, through personnel reorganization and operational restructuring. As a means of providing a roadmap to encourage other transplant centers to re-energize their pancreas transplant programs, we will outline strategies that can be readily instituted to transform a pancreas transplant program, and delineate the basic steps that any transplant center can take to achieve high-volume success. Summary The negative trends in access to pancreas transplantation in the US may ultimately be addressed by low-volume pancreas transplant programs re-committing themselves through easily achievable institutional changes without substantial added capital investment, thereby maximizing access to pancreas transplantation for their diabetic patients and maintaining excellent outcomes.
引用
收藏
页码:440 / 447
页数:8
相关论文
共 27 条
  • [1] Comparison before and after transplantation of pancreas-kidney and pancreas-kidney with loss of pancreas - A prospective controlled quality of life study
    Adang, EMM
    Engel, GL
    vanHooff, JP
    Kootstra, G
    [J]. TRANSPLANTATION, 1996, 62 (06) : 754 - 758
  • [2] Al-Qaoud T, 2017, CASE SIMULTANEOUS PA
  • [3] Transplant Center Volume and the Risk of Pancreas Allograft Failure
    Alhamad, Tarek
    Malone, Andrew F.
    Brennan, Daniel C.
    Stratta, Robert J.
    Chang, Su-Hsin
    Wellen, Jason R.
    Horwedel, Timothy A.
    Lentine, Krista L.
    [J]. TRANSPLANTATION, 2017, 101 (11) : 2757 - 2764
  • [4] Evidence-Informed Clinical Practice Recommendations for Treatment of Type 1 Diabetes Complicated by Problematic Hypoglycemia
    Choudhary, Pratik
    Rickels, Michael R.
    Senior, Peter A.
    Vantyghem, Marie-Christine
    Maffi, Paola
    Kay, Thomas W.
    Keymeulen, Bart
    Inagaki, Nobuya
    Saudek, Frantisek
    Lehmann, Roger
    Hering, Bernhard J.
    [J]. DIABETES CARE, 2015, 38 (06) : 1016 - 1029
  • [5] Chu Q, 2018, HEPATOPANCREATOBILIA, P911
  • [6] Virtual HLA Crossmatching as a Means to Safely Expedite Transplantation of Imported Pancreata
    Eby, Brian C.
    Redfield, Robert R.
    Ellis, Thomas M.
    Leverson, Glen E.
    Schenian, Abby R.
    Odorico, Jon S.
    [J]. TRANSPLANTATION, 2016, 100 (05) : 1103 - 1110
  • [7] A Composite Risk Model for Predicting Technical Failure in Pancreas Transplantation
    Finger, E. B.
    Radosevich, D. M.
    Dunn, T. B.
    Chinnakotla, S.
    Sutherland, D. E. R.
    Matas, A. J.
    Pruett, T. L.
    Kandaswamy, R.
    [J]. AMERICAN JOURNAL OF TRANSPLANTATION, 2013, 13 (07) : 1840 - 1849
  • [8] No Difference in Transplant Outcomes for Local and Import Pancreas Allografts
    Fridell, Jonathan A.
    Mangus, Richard S.
    Hollinger, Edward F.
    Milgrom, Martin L.
    Taber, Tim E.
    Mohler, Elaine
    Good, Jason
    Goble, Michelle L.
    Powelson, John A.
    [J]. TRANSPLANTATION, 2009, 88 (05) : 723 - 728
  • [9] Gross CR, 1998, CLIN TRANSPLANT, V12, P351
  • [10] Outcomes of Preemptive Kidney With or Without Subsequent Pancreas Transplant Compared With Preemptive Simultaneous Pancreas/Kidney Transplantation
    Huang, Edmund
    Wiseman, Alexander
    Okumura, Sean
    Kuo, Hung-Tien
    Bunnapradist, Suphamai
    [J]. TRANSPLANTATION, 2011, 92 (10) : 1115 - 1122