Immune Checkpoint Therapy in Melanoma

被引：11

作者：

Callahan, Margaret K. ^{[1
,2
]}

机构：

[1] Mem Sloan Kettering Canc Ctr, Dept Med, Melanoma & Immunotherapy Serv, New York, NY 10065 USA

[2] Cornell Univ, Weill Med Coll, New York, NY 10021 USA

来源：

CANCER JOURNAL | 2016年 / 22卷 / 02期

关键词：

Checkpoint-blocking antibodies; immune checkpoint therapy; metastatic melanoma; T-CELL RESPONSES; CTLA-4; BLOCKADE; IPILIMUMAB TREATMENT; ANTI-PD-L1; ANTIBODY; NIVOLUMAB; SAFETY; EFFICACY; PEMBROLIZUMAB; COMBINATION; DABRAFENIB;

D O I：

10.1097/PPO.0000000000000183

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Checkpoint-blocking antibodies have transformed cancer therapy, and the treatment of patients with metastatic melanoma has led the revolution. Herein, we review the current clinical data supporting the use of checkpoint-blocking antibodies in the treatment of melanoma and highlight outstanding clinical questions and unmet clinical needs.

引用

页码：73 / 80

页数：8

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