Long-term follow-up of trigeminal neuralgia treatment using a linear accelerator

被引:20
作者
Kubicek, GJ
Hall, WA
Orner, JB
Gerbi, BJ
Dusenbery, KE
机构
[1] Univ Minnesota, Dept Therapeut Radiol Radiat Oncol, Minneapolis, MN USA
[2] Univ Minnesota, Dept Neurosurg, Minneapolis, MN 55455 USA
关键词
trigeminal neuralgia; linear accelerator; radiosurgery; trigeminal nerve;
D O I
10.1159/000083176
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
While most of the studies examining radiosurgery for trigeminal neuralgia have used a Gamma Knife, a linear accelerator can also be utilized for treatment. We report on 20 patients with trigeminal neuralgia who received 23 treatments with a linear accelerator that delivered a maximum dose of 82.3 - 100 Gy. The median patient follow- up was 56.5 months, 70% of patients had received previous surgical treatment and 20% had secondary ( nonessential) trigeminal neuralgia. Eight ( 35%) radiosurgery treatments resulted in complete pain relief; 5 ( 63%) patients with initial pain relief had pain recurrence at a mean time of 21.5 months. Ten ( 43%) patients reported a 50% or more decrease in pain severity but have not achieved a pain- free state. A total of 18 ( 78%) treatments resulted in no pain or a 50% or greater improvement in pain. Five treatments ( 22%) resulted in less than 50% improvement in pain. We conclude that linear accelerator stereotactic radiosurgery is a viable treatment option for trigeminal neuralgia patients, especially for patients who have not had a previous invasive treatment. Copyright (C) 2004 S. Karger AG, Basel.
引用
收藏
页码:244 / 249
页数:6
相关论文
共 17 条
  • [1] The long-term outcome of microvascular decompression for trigeminal neuralgia
    Barker, FG
    Jannetta, PJ
    Bissonette, DJ
    Larkins, MV
    Jho, HD
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1996, 334 (17) : 1077 - 1083
  • [2] Long-term outcome after operation for trigeminal neuralgia in patients with posterior fossa tumors
    Barker, FG
    Jannetta, PJ
    Babu, RP
    Pomonis, S
    Bissonette, DJ
    Jho, HD
    [J]. JOURNAL OF NEUROSURGERY, 1996, 84 (05) : 818 - 825
  • [3] Microvascular decompression for trigeminal neuralgia: comments on a series of 250 cases, including 10 patients with multiple sclerosis
    Broggi, G
    Ferroli, P
    Franzini, A
    Servello, D
    Dones, I
    [J]. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2000, 68 (01) : 59 - 64
  • [4] BRYAN GW, 2003, NEUROSURGERY, V53, P823
  • [5] Pathophysiology of trigeminal neuralgia: The ignition hypothesis
    Devor, M
    Amir, R
    Rappaport, ZH
    [J]. CLINICAL JOURNAL OF PAIN, 2002, 18 (01) : 4 - 13
  • [6] Microvascular decompression
    Elias, WJ
    Burchiel, KJ
    [J]. CLINICAL JOURNAL OF PAIN, 2002, 18 (01) : 35 - 41
  • [7] Gamma knife radiosurgery for trigeminal neuralgia -: Results and expectations
    Kondziolka, D
    Perez, B
    Flickinger, JC
    Habeck, M
    Lunsford, LD
    [J]. ARCHIVES OF NEUROLOGY, 1998, 55 (12) : 1524 - 1529
  • [8] Clinical outcomes after stereotactic radiosurgery for idiopathic trigeminal neuralgia
    Maesawa, S
    Salame, C
    Flickinger, JC
    Pirris, S
    Kondziolka, D
    Lunsford, LD
    [J]. JOURNAL OF NEUROSURGERY, 2001, 94 (01) : 14 - 20
  • [9] PERCUTANEOUS MICROCOMPRESSION OF THE TRIGEMINAL GANGLION FOR TRIGEMINAL NEURALGIA
    MULLAN, S
    LICHTOR, T
    [J]. JOURNAL OF NEUROSURGERY, 1983, 59 (06) : 1007 - 1012
  • [10] Gamma knife radiosurgery using 90 Gy for trigeminal neuralgia
    Nicol, B
    Regine, WF
    Courtney, C
    Meigooni, A
    Sanders, M
    Young, B
    [J]. JOURNAL OF NEUROSURGERY, 2000, 93 : 152 - 154