Cu(OTf)2:: a reusable catalyst for high-yield synthesis of 3,4-dihydropyrimidin-2(1H)-ones

被引：378

作者：

Paraskar, AS ^{[1
]}

Dewkar, GK ^{[1
]}

Sudalai, A ^{[1
]}

机构：

[1] Natl Chem Lab, Proc Dev Div, Pune 411008, Maharashtra, India

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 16期

关键词：

aldehydes; Biginelli reactions; catalysts; 3,4-dihydropyrimidin-2(IH)-ones; copper and compounds;

D O I：

10.1016/S0040-4039(03)00619-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Copper(II) triflate catalyzes efficiently the three-component condensation reaction of an aldehyde, beta-ketoester and urea in acetonitrile to afford the corresponding 3,4-dihydropyrimidin-2(1H)-ones in high yields. The catalyst exhibited remarkable reusable activity. (C) 2003 Elsevier Science Ltd. All rights reserved.

引用

页码：3305 / 3308

页数：4

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