CSN5A Subunit of COP9 Signalosome Is Required for Resetting Transcriptional Stress Memory after Recurrent Heat Stress in Arabidopsis

被引:16
作者
Singh, Amit Kumar [1 ]
Dhanapal, Shanmuhapreya [1 ]
Finkelshtein, Alin [2 ]
Chamovitz, Daniel A. [1 ,2 ]
机构
[1] Ben Gurion Univ Negev, Jacob Blaustein Inst Desert Res, IL-8499000 Midreshet Ben Gurion, Israel
[2] Tel Aviv Univ, Sch Plant Sci & Food Secur, IL-6997801 Tel Aviv, Israel
基金
以色列科学基金会;
关键词
COP9; signalosome; hypomorphic mutant; transcriptional stress memory; histone methylation; recurrent heat stress; LIGHT CONTROL; COMPLEX; GENE; REGULATOR; INTERACTS; CHROMATIN; NEDD8;
D O I
10.3390/biom11050668
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In nature, plants are exposed to several environmental stresses that can be continuous or recurring. Continuous stress can be lethal, but stress after priming can increase the tolerance of a plant to better prepare for future stresses. Reports have suggested that transcription factors are involved in stress memory after recurrent stress; however, less is known about the factors that regulate the resetting of stress memory. Here, we uncovered a role for Constitutive Photomorphogenesis 5A (CSN5A) in the regulation of stress memory for resetting transcriptional memory genes (APX2 and HSP22) and H3K4me3 following recurrent heat stress. Furthermore, CSN5A is also required for the deposition of H3K4me3 following recurrent heat stress. Thus, CSN5A plays an important role in the regulation of histone methylation and transcriptional stress memory after recurrent heat stress.
引用
收藏
页数:11
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