Enantioselective epoxidation of isoflavones by Jacobsen's Mn(III)salen catalysts and dimethyldioxirane oxygen-atom source

被引：29

作者：

Adam, W

Fell, RT

Lévai, A

Patonay, T

Peters, K

Simon, A

Tóth, G

机构：

[1] Lajos Kossuth Univ, Dept Organ Chem, H-4010 Debrecen, Hungary

[2] Univ Wurzburg, Inst Organ Chem, D-97074 Wurzburg, Germany

[3] Max Planck Inst Festkorperforsch, D-70506 Stuttgart, Germany

[4] Tech Univ Budapest, Inst Gen & Analyt Chem, Hungarian Acad Sci, Tech Analyt Res Grp, H-1111 Budapest, Hungary

来源：

TETRAHEDRON-ASYMMETRY | 1998年 / 9卷 / 07期

基金：

匈牙利科学研究基金会;

关键词：

D O I：

10.1016/S0957-4166(98)00102-5

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The catalytic enantioselective epoxidation of the isoflavones 1a-f has been performed by the Mn(III)salen complexes (R,R)-3 and (S,S)-3 as catalysts and dimethyldioxirane as the oxygen-atom source to afford optically active isoflavone epoxides 2a-f, The absolute configuration of the nonracemic epoxides 2 have been determined by X-ray diffraction analysis. Our present results constitute the first examples of the preparation of optically active isoflavone epoxides. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：1121 / 1124

页数：4

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