Gynecologic Cancer InterGroup (GCIG) Consensus Review for Mucinous Ovarian Carcinoma

被引：71

作者：

Ledermann, Jonathan A. ^{[1
,2
]}

Luvero, Daniela ^{[1
,2
]}

Shafer, Aaron ^{[3
]}

O'Connor, Dennis ^{[4
]}

Mangili, Giorgia ^{[5
]}

Friedlander, Michael ^{[6
]}

Pfisterer, Jacobus ^{[7
]}

Mirza, Mansoor R. ^{[8
]}

Kim, Jae-Weon ^{[9
]}

Alexandre, Jerome ^{[10
]}

Oza, Amit ^{[11
]}

Brown, Jubilee ^{[12
]}

机构：

[1] UCL Canc Inst, London W1T 4TJ, England

[2] UCL Hosp, London, England

[3] Hartford Hosp, Hartford, CT 06115 USA

[4] Univ Louisville, Sch Med, Louisville, KY 40292 USA

[5] IRCCS San Raffaele Hosp, Milan, Italy

[6] Prince Wales Hosp Randwick, Randwick, NSW, Australia

[7] Gynecol Oncol Ctr, Kiel, Germany

[8] Copenhagen Univ Hosp, Rigshosp, Copenhagen, Denmark

[9] Seoul Natl Univ, Coll Med, Seoul, South Korea

[10] Paris Descartes Univ, Cochin Hotel Dieu, Paris, France

[11] Princess Margaret Hosp, Toronto, ON M4X 1K9, Canada

[12] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA

来源：

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER | 2014年 / 24卷 / 09期

关键词：

Mucinous ovarian cancer; Mucinous tumor; BORDERLINE TUMORS; INTESTINAL-TYPE; CHEMOTHERAPY; WOMEN; ADENOCARCINOMAS; PREVALENCE; MUTATIONS; SUBTYPES;

D O I：

10.1097/IGC.0000000000000296

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Mucinous carcinomas of the ovary can be primary or metastatic in origin. Improvements in the pathological diagnosis have increased the ability to distinguish between primary and metastatic ovarian cancers and shown that primary mucinous carcinomas are a rare subtype of ovarian cancer. Most tumors are diagnosed at an early stage, and the prognosis after surgery is good. Advanced or recurrent mucinous carcinoma of the ovary responds poorly to current cytotoxic treatments, and the prognosis is poor. Here, we review the guidelines for surgery and the results of treatment of advanced and recurrent disease. Chemotherapy with platinum and paclitaxel is currently used to treat advanced disease, but the effect of these drugs is modest, and new treatments are needed.

引用

页码：S14 / S19

页数：6

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