Gastrointestinal stromal tumors of the small intestine that expressed c-kit protein

We report two patients with gastrointestinal stromal tumors (GISTs) of the small intestine that expressed c-kit protein (CD117), One was a 68-year-old woman with epigastralgia and vomiting. A submucosal turner of the upper jejunum was detected, and partial resection was carried out, The histology revealed a GIST negative for CD34 but positive for CD117, The other was a 42-year-old woman with progressive anemia, melena and lower abdominal pain, Intussusception was detected, and a partial resection was carried out. A submucosal tumor of the lower jejunum was noted. The histology revealed a GIST positive for both CD34 and CD117.