Chiral separation of hesperidin and naringin and its analysis in a butanol extract of Launeae arborescens

被引：24

作者：

Belboukhari, Nasser ^{[1
,2
]}

Cheriti, Abdelkrim ^{[1
]}

Roussel, Christian ^{[2
]}

Vanthuyne, Nicolas ^{[2
]}

机构：

[1] Univ Bechar, Phytochem & Organ Synth Lab, Bechar 08000, Algeria

[2] Univ Paul Cezanne, UMR Chirotechnol Catalyse & Biocatalyse, F-13397 Marseille 20, France

来源：

NATURAL PRODUCT RESEARCH | 2010年 / 24卷 / 07期

关键词：

Launeae arborescens; Asteraceae; hesperidin; naringin; flavanone; diastereomerisation barriers; enantioselective HPLC; CAPILLARY-ELECTROPHORESIS; LIQUID-CHROMATOGRAPHY; HPLC SEPARATION; CITRUS JUICES; FLAVANONE-7-O-GLYCOSIDES; DIASTEREOMERS; FLAVANONES; ENANTIOMERS; BARRIER;

D O I：

10.1080/14786410903178376

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Two flavanone glycosides were isolated from the aerial part of Launeae arborescens (Asteraceae), which were identified as hesperidin and naringin. They are the most abundant flavonoids in the edible parts of many species of citrus fruits. In this study, we were interested in the chiral separation and determination of the diastereomerisation barriers of hesperidin and naringin by HPLC methods. The chiral separation HPLC screening of diastereomers of hesperidin and naringin by HPLC methods was accomplished in the normal-phase mode using 11 chiral stationary phases and various n-hexane/alcohol mobile phases. The rate constants and activation energy of diastereomerisation (G#) of flavanones, naringin and hesperidin were determined, respectively, on Chiralpak IC and Chiralpak IA. The analysis of flavanones isolated in butanol extracts of Launeae arborescens were confirmed by HPLC on Chiralpak IC.

引用

页码：669 / 681

页数：13

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