Mechanisms of Acquired Resistance to AZD9291 in EGFR T790M Positive Lung

被引：0

作者：

Oxnard, Geoffrey R. ^{[1
]}

Thress, Kenneth ^{[2
]}

Paweletz, Cloud ^{[1
]}

Stetson, Daniel ^{[2
]}

Dougherty, Brian ^{[2
]}

Lai, Zhongwu ^{[2
]}

Markovets, Aleksandra ^{[2
]}

Felip, Enriqueta ^{[3
]}

Vivancos, Ana ^{[4
]}

Kuang, Yanan ^{[1
]}

Sholl, Lynette ^{[5
]}

Redig, Amanda J. ^{[1
]}

Cantarini, Mireille ^{[6
]}

Barrett, J. Carl ^{[2
]}

Pillai, Rathi N. ^{[7
]}

Cho, Byoung Chul ^{[8
]}

Lacroix, Ludovic ^{[9
]}

Planchard, David ^{[9
]}

Soria, Jean Charles ^{[9
]}

Jaenne, Pasi A. ^{[1
]}

机构：

[1] Dana Farber Canc Inst, Boston, MA 02115 USA

[2] Astrazeneca, Waltham, MA USA

[3] Vall DHebron Univ Hosp, Barcelona, Spain

[4] Vall DHebron Inst Oncol, Barcelona, Spain

[5] Brigham & Womens Hosp, Boston, MA 02115 USA

[6] Astrazeneca, Macclesfield, Cheshire, England

[7] Emory Univ, Winship Canc Inst, Atlanta, GA 30322 USA

[8] Yonsei Canc Ctr, Seoul, South Korea

[9] Gustave Roussy, Villejuif, France

来源：

JOURNAL OF THORACIC ONCOLOGY | 2015年 / 10卷 / 09期

关键词：

AZD9291; EGFR-TKI; T790M;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

ORAL17.07

引用

页码：S207 / S207

页数：1

共 50 条

[1] EGFR-independent mechanisms of acquired resistance to AZD9291 in EGFR T790M-positive NSCLC patients
Planchard, D.
Loriot, Y.
Andre, F.
Gobert, A.
Auger, N.
Lacroix, L.
Soria, J. C.
ANNALS OF ONCOLOGY, 2015, 26 (10) : 2073 - 2078
[2] Structural Basis of AZD9291 Selectivity for EGFR T790M
Yan, Xiao-E
Ayaz, Pelin
Zhu, Su-Jie
Zhao, Peng
Liang, Ling
Zhang, Casey H.
Wu, Ya-Chuang
Li, Je-Luen
Choi, Hwan Geun
Huang, Xin
Shan, Yibing
Shaw, David E.
Yun, Cai-Hong
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 63 (15) : 8502 - 8511
[3] Acquired EGFR C797S mutation mediates resistance to AZD9291 in non–small cell lung cancer harboring EGFR T790M
Kenneth S Thress
Cloud P Paweletz
Enriqueta Felip
Byoung Chul Cho
Daniel Stetson
Brian Dougherty
Zhongwu Lai
Aleksandra Markovets
Ana Vivancos
Yanan Kuang
Dalia Ercan
Sarah E Matthews
Mireille Cantarini
J Carl Barrett
Pasi A Jänne
Geoffrey R Oxnard
Nature Medicine, 2015, 21 : 560 - 562
[4] Successful AZD9291 Therapy Based on Circulating T790M
Gautschi, Oliver
Aebi, Stefan
Heukamp, Lukas C.
JOURNAL OF THORACIC ONCOLOGY, 2015, 10 (12) : E122 - E124
[5] Acquired EGFR C797S mutation mediates resistance to AZD9291 in non-small cell lung cancer harboring EGFR T790M
Thress, Kenneth S.
Paweletz, Cloud P.
Felip, Enriqueta
Cho, Byoung Chul
Stetsonl, Daniel
Dougherty, Brian
Lai, Zhongwu
Markovets, Aleksandra
Vivancos, Ana
Kuang, Yanan
Ercan, Dalia
Matthews, Sarah E.
Cantarini, Mireille
Barrett, J. Carl
Jaenne, Pasi A.
Oxnard, Geoffrey R.
NATURE MEDICINE, 2015, 21 (06) : 560 - 562
[6] AZD9291, an Irreversible EGFR TKI, Overcomes T790M-Mediated Resistance to EGFR Inhibitors in Lung Cancer
Cross, Darren A. E.
Ashton, Susan E.
Ghiorghiu, Serban
Eberlein, Cath
Nebhan, Caroline A.
Spitzler, Paula J.
Orme, Jonathon P.
Finlay, M. Raymond V.
Ward, Richard A.
Mellor, Martine J.
Hughes, Gareth
Rahi, Amar
Jacobs, Vivien N.
Brewer, Monica Red
Ichihara, Eiki
Sun, Jing
Jin, Hailing
Ballard, Peter
Al-Kadhimi, Katherine
Rowlinson, Rachel
Klinowska, Teresa
Richmond, Graham H. P.
Cantarini, Mireille
Kim, Dong-Wan
Ranson, Malcolm R.
Pao, William
CANCER DISCOVERY, 2014, 4 (09) : 1046 - 1061
[7] Osimertinib (AZD9291) increases radio-sensitivity in EGFR T790M non-small cell lung cancer
Wang, Nannan
Wang, Linlin
Meng, Xiangjiao
Wang, Jia
Zhu, Lifang
Liu, Changting
Li, Shaorong
Zheng, Li
Yang, Zhenfan
Xing, Ligang
Yu, Jinming
ONCOLOGY REPORTS, 2019, 41 (01) : 77 - 86
[8] Rapid clearance of circulating tumor DNA during treatment with AZD9291 of a lung cancer patient presenting the resistance EGFR T790M mutation
Vallee, Audrey
Audigier-Valette, Clarisse
Herbreteau, Guillaume
Merrien, Julien
Tessonnier, Laurent
Theoleyre, Sandrine
Denis, Marc G.
LUNG CANCER, 2016, 91 : 73 - 74
[9] Overcoming acquired resistance of gefitinib in lung cancer cells without T790M by AZD9291 or Twist1 knockdown in vitro and in vivo
Liu, Zhongwei
Gao, Weimin
ARCHIVES OF TOXICOLOGY, 2019, 93 (06) : 1555 - 1571
[10] Temporal changes of EGFR mutations and T790M levels in tumour and plasma DNA following AZD9291 treatment
Chia, Puey Ling
Do, Hongdo
Morey, Adrienne
Mitchell, Paul
Dobrovic, Alexander
John, Thomas
LUNG CANCER, 2016, 98 : 29 - 32

← 1 2 3 4 5 →