Current status of the management of symptomatic intracranial atherosclerotic disease: the rationale for a randomized trial of medical therapy and intracranial stenting

被引：6

作者：

Fiorella, D. ^{[1
]}

Turan, T. N. ^{[2
]}

Derdeyn, C. P. ^{[3
]}

Chimowitz, M. I. ^{[2
]}

机构：

[1] SUNY Stony Brook, Med Ctr, Dept Neurosurg, New York, NY USA

[2] Med Univ S Carolina, Div Neurol, Charleston, SC 29425 USA

[3] Washington Univ, Div Radiol Neurol & Neurosurg, St Louis, MO USA

来源：

JOURNAL OF NEUROINTERVENTIONAL SURGERY | 2009年 / 1卷 / 01期

关键词：

TRANSIENT ISCHEMIC ATTACK; ANTITHROMBOTIC THERAPY; AGGRESSIVE REDUCTION; STROKE PREVENTION; WINGSPAN STENT; ANGIOPLASTY; STENOSIS; ASPIRIN; RISK; COMPLICATIONS;

D O I：

10.1136/jnis.2009.000125

中图分类号：

R445 [影像诊断学];

学科分类号：

100207 ;

摘要：

Stenting and Aggressive Medical Management for Preventing Recurrent stroke in Intracranial Stenosis (SAMMPRIS) is a randomized trial comparing aggressive medical management alone with aggressive medical management in combination with angioplasty and stenting using the Gateway-Wingspan system in patients with symptomatic, high-grade, intracranial stenosis. This trial represents a landmark in the maturation of the field of neurointervention, establishing a foundation for evidenced-based practice. We review the natural history of symptomatic intracranial stenosis when treated medically, the available interventional therapies and the rationale for the design of the SAMMPRIS trial.

引用

页码：35 / 39

页数：5

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