Forensic implications of genetic analyses from degraded DNA-A review

被引：241
作者：
Alaeddini, Reza [3 ]
Walsh, Simon J. [1 ,2 ]
Abbas, Ali [3 ]
机构：
[1] Australian Fed Police, Forens Ctr, Canberra, ACT, Australia
[2] Australian Fed Police, Ctr Data, Canberra, ACT, Australia
[3] Univ Sydney, Sch Chem & Biomol Engn, Sydney, NSW 2006, Australia
来源：
FORENSIC SCIENCE INTERNATIONAL-GENETICS | 2010年 / 4卷 / 03期
关键词：
DNA degradation; Forensics; Cell death; Deoxyribonuclease; PCR; WHOLE GENOME AMPLIFICATION; PROGRAMMED CELL-DEATH; MITOCHONDRIAL-DNA; COPY-NUMBER; HUMAN REMAINS; ANCIENT DNA; DEOXYRIBONUCLEIC-ACID; MOLECULAR-CLONING; MISCODING LESIONS; SKELETAL REMAINS;
D O I：
10.1016/j.fsigen.2009.09.007
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Forensic DNA identification techniques are principally based on determination of the size or sequence of desired PCR products. The fragmentation of DNA templates or the structural modifications that can occur during the decomposition process can impact the outcomes of the analytical procedures. This study reviews the pathways involved in cell death and DNA decomposition and the subsequent difficulties these present in DNA analysis of degraded samples. (C) 2009 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码：148 / 157
页数：10
相关论文
共 155 条
[1]   Real-time PCR designs to estimate nuclear and mitochondrial DNA copy number in forensic and ancient DNA studies [J].
Alonso, A ;
Martín, P ;
Albarrán, C ;
García, P ;
García, O ;
de Simón, LF ;
García-Hirschfeld, J ;
Sancho, M ;
de la Rúa, C ;
Fernández-Piqueras, J .
FORENSIC SCIENCE INTERNATIONAL, 2004, 139 (2-3) :141-149
[2]  
Alonso A, 2003, CROAT MED J, V44, P273
[3]  
Andelinovic S, 2005, CROAT MED J, V46, P530
[4]   DNA DECOMPOSITION BY SOIL MICROORGANISMS [J].
ANTHEUNISSE, J .
ANTONIE VAN LEEUWENHOEK JOURNAL OF MICROBIOLOGY AND SEROLOGY, 1971, 37 (02) :258-+
[5]   DECOMPOSITION OF NUCLEIC-ACIDS AND SOME OF THEIR DEGRADATION PRODUCTS BY MICROORGANISMS [J].
ANTHEUNISSE, J .
ANTONIE VAN LEEUWENHOEK JOURNAL OF MICROBIOLOGY AND SEROLOGY, 1972, 38 (03) :311-+
[6]  
ANZAI N, 1995, BLOOD, V86, P917
[7]   Amplification efficiency of thermostable DNA polymerases [J].
Arezi, B ;
Xing, WM ;
Sorge, JA ;
Hogrefe, HH .
ANALYTICAL BIOCHEMISTRY, 2003, 321 (02) :226-235
[8]   Analysis of gene-specific DNA damage and repair using quantitative polymerase chain reaction [J].
Ayala-Torres, S ;
Chen, YM ;
Svoboda, T ;
Rosenblatt, J ;
Van Houten, B .
METHODS, 2000, 22 (02) :135-147
[9]   Preservation of key biomolecules in the fossil record: current knowledge and future challenges [J].
Bada, JL ;
Wang, XYS ;
Hamilton, H .
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES, 1999, 354 (1379) :77-86
[10]   Human Deoxyribonucleases [J].
Baranovskii, AG ;
Buneva, VN ;
Nevinsky, GA .
BIOCHEMISTRY-MOSCOW, 2004, 69 (06) :587-601
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