Accuracy of diffusion-weighted MR imaging in the diagnosis of sporadic Creutzfeldt-Jakob disease

被引：68
作者：
Demaerel, P
Sciot, R
Robberecht, W
Dom, R
Vandermeulen, D
Maes, F
Wilms, G
机构：
[1] Katholieke Univ Leuven Hosp, Dept Radiol, B-3000 Louvain, Belgium
[2] Katholieke Univ Leuven Hosp, Dept Med Imaging Comp, B-3000 Louvain, Belgium
[3] Katholieke Univ Leuven Hosp, Dept Neurol, B-3000 Louvain, Belgium
来源：
JOURNAL OF NEUROLOGY | 2003年 / 250卷 / 02期
关键词：
Creutzfeldt-Jakob disease; diffusion-weighted imaging; brain; MR imaging;
D O I：
10.1007/s00415-003-0983-6
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
The definitive diagnosis of sporadic Creutzfeldt-Jakob disease (sCJD) is based on brain autopsy. The 14-3-3 analysis in the CSF is considered a highly sensitive and specific procedure. Sensitivity, specificity and accuracy of EEG, the 14-3-3 assay and MR imaging in 12 patients referred for suspected sCJD were calculated. We suggest that diffusion-weighted MR imaging (DWI) should be included in the array of diagnostic tests because of the 100 % sensitivity and specificity.
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页码：222 / 225
页数：4
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